Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10048705 | 0.89 | GAA (0.49) | GAAKDM4ELMNAMAPK1BRAF | |
| SCHEMBL10048709 | 0.86 | BRD4 (0.50) | GAAKDM4ELMNAMAPK1BRAF | |
| SCHEMBL10048658 | 0.86 | GAA (0.47) | GAAKDM4ELMNAMAPK1BRAF | |
| SCHEMBL10048678 | 0.86 | GAA (0.46) | GAAKDM4ELMNAMAPK1BRAF | |
| SCHEMBL10049210 | 0.86 | BRD4 (0.44) | GAAKDM4ELMNAMAPK1BRAF | |
| SCHEMBL10049223 | 0.85 | GAA (0.46) | GAAKDM4ELMNAMAPK1BRAF | |
| SCHEMBL14963720 | 0.84 | GAA (0.47) | GAAKDM4ELMNAMAPK1BRAF | |
| SCHEMBL10048662 | 0.84 | GAA (0.45) | GAAKDM4ELMNAMAPK1BRAF | |
| SCHEMBL10048692 | 0.84 | BRD4 (0.44) | GAAKDM4ELMNAMAPK1BRAF | |
| SCHEMBL14963722 | 0.84 | BRAF (0.46) | GAAKDM4ELMNAMAPK1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018665-A1 | FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |