Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 4/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14963735 | 0.90 | KDM4E (0.45) | KDM4EGAAALDH1A1HPGDALOX15 | |
| SCHEMBL10048708 | 0.84 | BRAF (0.43) | KDM4EGAAALDH1A1HPGDATM | |
| SCHEMBL10048883 | 0.82 | GAA (0.47) | KDM4EGAAALDH1A1HPGDCASP1 | |
| SCHEMBL14963777 | 0.81 | ATM (0.40) | KDM4EGAAALDH1A1HPGDALOX15 | |
| SCHEMBL14963762 | 0.81 | GAA (0.46) | KDM4EGAAALDH1A1HPGDCASP1 | |
| SCHEMBL14963727 | 0.79 | GAA (0.52) | KDM4EGAAALDH1A1HPGDALOX15 | |
| SCHEMBL10048762 | 0.77 | GAA (0.52) | KDM4EGAAALDH1A1HPGDALOX15 | |
| SCHEMBL10049222 | 0.77 | KDM4E (0.53) | KDM4EGAAALDH1A1HPGDALOX15 | |
| SCHEMBL10049203 | 0.74 | GAA (0.49) | KDM4EGAAALDH1A1HPGDALOX15 | |
| SCHEMBL10048760 | 0.74 | GAA (0.49) | KDM4EGAAALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018665-A1 | FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |