⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22692966 | 0.85 | HTR1D (0.32) | — | |
| Hydrochloric Acid SCHEMBL23753479 | 0.77 | — | — | |
| SCHEMBL22401884 | 0.64 | — | — | |
| Bromide SCHEMBL28296934 | 0.61 | — | — | |
| SCHEMBL27398149 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL25342137 | 0.59 | BLM (0.41) | — | |
| SCHEMBL18134378 | 0.59 | HTR2C (0.31) | — | |
| SCHEMBL12550550 | 0.58 | — | — | |
| SCHEMBL7082999 | 0.58 | — | — | |
| SCHEMBL2221820 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057047-A | Synthesis of heterocyclic compounds from carboxamides and carboxamide derivatives and haloalkanols | 夸祖鲁-纳塔尔大学 | 2023-05-02 | — | — | CN | disclosed |
| US-20190134056-A1 | K-RAS MUTATIONS AND ANTAGONISTS | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOG (US) | 2019-05-09 | — | — | US | disclosed |
| US-20170135926-A1 | TOPICAL COMPOSITIONS AND METHODS FOR SKIN LIGHTENING | AVON PROD INC (US) | 2017-05-18 | — | — | US | disclosed |
| US-20170135926-A1 | TOPICAL COMPOSITIONS AND METHODS FOR SKIN LIGHTENING | AVON PROD INC (US) | 2017-05-18 | — | — | US | disclosed |
| US-9592186-B2 | Topical compositions and methods for skin lightening | AVON PRODUCTS, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-9592186-B2 | Topical compositions and methods for skin lightening | AVON PRODUCTS, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-9566224-B2 | Tyrosinase inhibitors | AVON PRODUCTS, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-9566224-B2 | Tyrosinase inhibitors | AVON PRODUCTS, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-20160263006-A1 | TOPICAL COMPOSITIONS AND METHODS FOR SKIN LIGHTENING | AVON PRODUCTS, INC. | 2016-09-15 | — | — | US | disclosed |
| US-9364405-B2 | Tyrosinase inhibitors | AVON PRODUCTS, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150174034-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC. | 2015-06-25 | — | — | US | disclosed |
| US-20150164758-A1 | TYROSINASE INHIBITORS | CITIBANK, N.A., LONDON BRANCH | 2015-06-18 | — | — | US | disclosed |
| US-20150152122-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC. | 2015-06-04 | — | — | US | disclosed |
| US-20150118170-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC. | 2015-04-30 | — | — | US | disclosed |
| US-20150111897-A1 | TYROSINASE INHIBITORS | NEW AVON LLC | 2015-04-23 | — | — | US | disclosed |
| US-8394427-B2 | Paxillin stimulating compositions and cosmetic uses thereof | AVON PRODUCTS, INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120328546-A1 | Paxillin Stimulating Compositions and Cosmetic Uses Thereof | AVON PRODUCTS, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| US-8168212-B2 | Topical compositions comprising non-proteogenic amino acids and methods of treating skin | AVON PRODUCTS, INC (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110151029-A1 | Paxillin Stimulating Compositions and Cosmetic Uses Thereof | AVON PRODUCTS, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-20100261769-A1 | Topical Compositions Comprising Non-Proteogenic Amino Acids and Methods of Treating Skin | AVON PRODUCTS, INC. (US) | 2010-10-14 | — | — | US | disclosed |