Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 11/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.43 |
| ▸ | NPY4R | P50391 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16455129 | 1.00 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL14887385 | 1.00 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL17236056 | 1.00 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL24094770 | 0.93 | SIRT2 (0.44) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL20442348 | 0.92 | SIRT2 (0.45) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL18823483 | 0.92 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL22507679 | 0.92 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL19456862 | 0.91 | SIRT2 (0.42) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL24224697 | 0.91 | SIRT2 (0.42) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL15606256 | 0.91 | SIRT2 (0.42) | SIRT2SIRT1SIRT3SIRT5NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014151030-A1 | CELL PROLIFERATION INHIBITORS AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2014-09-25 | — | — | WO | disclosed |
| EP-1926757-B1 | ANTIBODY-COMB POLYMER CONJUGATE | UCB PHARMA SA (BE) | 2012-02-22 | — | — | EP | disclosed |