SCHEMBL10052064

SCHEMBL10052064

NNc1nc(O)nc(NN)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
GAA P10253 8/20 0.41
KDM4E B2RXH2 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
AGTR1 P30556 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
DPP4 P27487 1/20 0.32
KDM5A P29375 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36741 0.83 MAPT (0.58) MAPTSMN1; SMN2GAAKDM4EMEN1
SCHEMBL2538145 0.82 MAPT (0.33) MAPTSMN1; SMN2GAAKDM4EMEN1
SCHEMBL13901041 0.75 MAPT (0.46) MAPTSMN1; SMN2GAAKDM4EMEN1
SCHEMBL5029069 0.73 MAPT (0.50) MAPTSMN1; SMN2GAAKDM4EMEN1
Phosphoric Acid SCHEMBL6254623 0.73 MAPT (0.44) MAPTSMN1; SMN2GAAKDM4EMEN1
SCHEMBL6851028 0.71 MAPT (0.48) MAPTSMN1; SMN2GAAKDM4EMEN1
SCHEMBL11211646 0.71
SCHEMBL11187119 0.70 GAA (0.35) MAPTSMN1; SMN2GAAKDM4EMEN1
SCHEMBL13295567 0.69 PDE4A (0.39) GAACA1CA2CA9CYP1A2
SCHEMBL6353329 0.69 GAA (0.59) MAPTSMN1; SMN2GAAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372190-B2 Ink set, inkjet recording method and recorded material FUJIFILM CORPORATION (JP) 2013-02-12 US disclosed
US-8114208-B2 Ink jet ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2012-02-14 US disclosed
US-8101011-B2 Mono- and diazo dyes including pyrazol-5-yl rings attached to the azo group; good shades (hues) in the primary colors; colorfastness; photostability; weatherproofing; heat resistance; waterproofing; oxidation/ozone resistance; chemical resistance; storage stability; printing;electrography; displays FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20100302305-A1 INK SET, INKJET RECORDING METHOD AND RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2010-12-02 US disclosed
US-20100231670-A1 SET FOR INK JET RECORDING, AND INK JET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-09-16 US disclosed
US-7758683-B2 Ink composition, ink set and recording method FUJIFILM CORPORATION (JP) 2010-07-20 US disclosed
US-7704311-B2 Ink composition, manufacturing method of ink, ink set, and recording method FUJIFILM CORPORATION (JP) 2010-04-27 US disclosed
US-20100063262-A1 PROCESS FOR PRODUCING 5-AMINOPYRAZOLE DERIVATIVE, AND AZO DYE FUJIFILM CORPORATION (JP) 2010-03-11 US disclosed
US-20090274839-A1 INK JET INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-11-05 US disclosed
US-7566362-B2 Ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2009-07-28 US disclosed
US-7553358-B2 Ink jet ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2009-06-30 US disclosed
US-7510605-B2 Dye ink, ink jet recording method, ink sheet, color toner and color filter FUJIFILM CORPORATION (JP) 2009-03-31 US disclosed
US-7507282-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-20090047430-A1 INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-02-19 US disclosed
US-20080274285-A1 INK JET INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2008-11-06 US disclosed
US-20080274283-A1 Coloring Matter, Ink, Ink, for Ink Jet, Ink Jet Recording Method, Color Toner, and Color Filter FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed
US-20080199615-A1 Dye, Ink, Ink Jet Recording Method, Ink Sheet, Color Toner and Color Filter FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20070109376-A1 Ink composition, ink set and recording method FUJIFILM CORPORATION 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063262-A1 PROCESS FOR PRODUCING 5-AMINOPYRAZOLE DERIVATIVE, AND AZO DYE H1-5, CYP3A5, IL5 MAPT 2451/4885SMN1; SMN2 4766/4885GAA 1130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.