SCHEMBL1005236

SCHEMBL1005236

BrC1CC1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6555519 1.00
SCHEMBL8402635 0.84
SCHEMBL8407068 0.84
SCHEMBL162348 0.80 KDM4E (0.46)
Hydrochloric Acid SCHEMBL9860724 0.76 KDM4E (0.42)
SCHEMBL1766440 0.72
SCHEMBL1766438 0.72
SCHEMBL15996673 0.72
SCHEMBL1766390 0.72
SCHEMBL10066645 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312373-B2 Cyclopropane skeleton monophosphine ligands, palladium complexes thereof, preparation methods and application NANKAI UNIVERSITY (CN) 2025-05-27 US claimed
EP-4471039-A1 CYCLOPROPANE SKELETON MONOPHOSPHINE LIGAND AND PALLADIUM COMPLEX THEREOF AS WELL AS PREPARATION METHOD AND USE THEREOF Nankai University (CN) 2024-12-04 EP claimed
US-20240376136-A1 CYCLOPROPANE SKELETON MONOPHOSPHINE LIGANDS, PALLADIUM COMPLEXES THEREOF, PREPARATION METHODS AND APPLICATION EXTRAORDINARY SYNERGY TECHNOLOGY (TIANJIN) CO., LTD (CN) 2024-11-14 US claimed
CN-118812603-A Cyclopropane monophosphine ligand-cobalt complex, preparation method and application 南开大学 2024-10-22 CN claimed
CN-118406198-A Matrix gel, microgel particles, self-reinforced injectable gel, and preparation method and application thereof 天津大学 2024-07-30 CN claimed
CN-118290748-A Amphiphilic polymer, dibromocyclopropane-based polymer, stress sensitive micelle and preparation method thereof 天津大学 2024-07-05 CN claimed
CN-118290338-A Building block 6-azaspiro [2.5] octane synthesized by Sovilnesib as anticancer medicine for clinical research and its synthesizing process 上海苏博医药科技有限公司 2024-07-05 CN claimed
CN-116535439-B Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof 南开大学 2024-05-28 CN claimed
CN-116535439-A Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof 南开大学 2023-08-04 CN claimed
WO-2023142725-A1 CYCLOPROPANE SKELETON MONOPHOSPHINE LIGAND AND PALLADIUM COMPLEX THEREOF AS WELL AS PREPARATION METHOD AND USE THEREOF 南开大学 2023-08-03 WO claimed
CN-113402358-A Novel synthesis method of cyclopropyl bromide 中昊(大连)化工研究设计院有限公司 2021-09-17 CN claimed
WO-2014064477-A1 PROCESS TO MAKE HIGHLY SUBSTITUTED INDENES USING METAL SLAT CATALYSTS ROSOCHA GREGORY (CA) 2014-05-01 WO claimed
US-4162233-A Isomerization-alkylation systems comprising a Gr. III A Lewis acid and a non-reactive aprotic solvent EXXON RESEARCH & ENGINEERING CO. (US) 1979-07-24 US claimed
EP-3433239-B1 SMALL MOLECULE INHIBITORS OF THE NUCLEAR TRANSLOCATION OF ANDROGEN RECEPTOR FOR THE TREATMENT OF CASTRATION-RESISTANT PROSTATE CANCER UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2026-05-27 EP disclosed
EP-4688144-A1 COMPOUNDS AS GLP-1R AGONISTS Terns Pharmaceuticals, Inc. (US) 2026-02-11 EP disclosed
US-20260015348-A1 COMPOUNDS AS GLP-1R AGONISTS TERNS PHARMACEUTICALS INC (US) 2026-01-15 US disclosed
US-4515727-A ANTIALLERGY, ANTINFLAMMATORY SYNTEX (U.S.A.) INC. (US) 1985-05-07 US disclosed
US-4229611-A Isomerization alkylation systems EXXON RESEARCH & ENGINEERING CO. (US) 1980-10-21 US disclosed
US-4162233-A Isomerization-alkylation systems comprising a Gr. III A Lewis acid and a non-reactive aprotic solvent EXXON RESEARCH & ENGINEERING CO. (US) 1979-07-24 US disclosed
US-3933768-A RUBBER BLENDS BRIDGESTONE TIRE COMPANY LIMITED (JA) 1976-01-20 US disclosed