⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14387952 | 1.00 | — | — | |
| SCHEMBL162371 | 1.00 | — | — | |
| Ethane SCHEMBL17938755 | 0.97 | CRBN (0.52) | — | |
| Succinic Acid SCHEMBL7441808 | 0.83 | CRBN (0.40) | — | |
| 2-Pyrrolidone SCHEMBL9744804 | 0.82 | OR51E2 (0.56) | — | |
| SCHEMBL13027236 | 0.76 | CRBN (0.40) | — | |
| SCHEMBL13058181 | 0.76 | CRBN (0.40) | — | |
| SCHEMBL6593198 | 0.76 | — | — | |
| SCHEMBL9398204 | 0.74 | — | — | |
| SCHEMBL493044 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295180-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
| WO-2017147240-A1 | HSP90 TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TARVEDA THERAPEUTICS, INC. (US) | 2017-08-31 | — | — | WO | disclosed |
| US-20170151339-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2017-06-01 | — | — | US | disclosed |
| EP-1940967-B1 | METHOD OF PRODUCING A METAL PHTHALOCYANINE COMPOUND, AND METHOD OF PRODUCING A PHTHALOCYANINE COMPOUND AND AN ANALOGUE THEREOF | FUJIFILM CORP (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-20120238563-A1 | NOVEL UNSATURATED TETRACYCLIC TETRAHYDROFURAN DERIVATIVES | CID-NUNEZ JOSE MARIA (ES) | 2012-09-20 | — | — | US | disclosed |
| US-20120238563-A1 | NOVEL UNSATURATED TETRACYCLIC TETRAHYDROFURAN DERIVATIVES | CID-NUNEZ JOSE MARIA (ES) | 2012-09-20 | — | — | US | disclosed |
| US-20120035170-A1 | NOVEL UNSATURATED TETRACYCLIC TETRAHYDROFURAN DERIVATIVES | NUNEZ JOSE MARIA (ES) | 2012-02-09 | — | — | US | disclosed |
| US-20120035170-A1 | NOVEL UNSATURATED TETRACYCLIC TETRAHYDROFURAN DERIVATIVES | NUNEZ JOSE MARIA (ES) | 2012-02-09 | — | — | US | disclosed |
| US-8022102-B2 | Unsaturated tetracyclic tetrahydrofuran derivatives | JANSSEN PHARMACEUTICA, NV (BE) | 2011-09-20 | — | — | US | disclosed |
| US-8022102-B2 | Unsaturated tetracyclic tetrahydrofuran derivatives | JANSSEN PHARMACEUTICA, NV (BE) | 2011-09-20 | — | — | US | disclosed |
| US-7902235-B2 | Compounds for nonsense suppression, and methods for their use | PTC THERAPEUTICS, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| US-20090203752-A1 | COMPOUNDS FOR NONSENSE SUPPRESSION, AND METHODS FOR THEIR USE | PTC THERAPEUTICS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| WO-2008153942-A1 | KINASE INHIBITOR COMPOUNDS | XCOVERY, INC. (US) | 2008-12-18 | — | — | WO | disclosed |
| US-20070191469-A1 | Novel tetracyclic tetrahydrofuran derivatives | JANSSEN-CILAG S.A. (ES) | 2007-08-16 | — | — | US | disclosed |
| US-20070191469-A1 | Novel tetracyclic tetrahydrofuran derivatives | JANSSEN-CILAG S.A. (ES) | 2007-08-16 | — | — | US | disclosed |