SCHEMBL10053547

SCHEMBL10053547

Cc1ccc(N(c2ccc(C)cc2)c2c(C)ccc3ccccc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.47
CYP1A2 P05177 5/20 0.47
TSHR P16473 5/20 0.47
ALDH1A1 P00352 4/20 0.41
L3MBTL1 Q9Y468 3/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
HPGD P15428 2/20 0.37
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HPRT1 P00492 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24283951 0.92 CYP1A2 (0.41) CYP2A6CYP1A2TSHRALDH1A1L3MBTL1
SCHEMBL28062983 0.89 CYP2A6 (0.50) CYP2A6CYP1A2TSHRALDH1A1L3MBTL1
SCHEMBL9162154 0.86 CYP1A2 (0.44) CYP2A6CYP1A2TSHRALDH1A1L3MBTL1
SCHEMBL28251669 0.86 CYP2A6 (0.44) CYP2A6CYP1A2TSHRALDH1A1L3MBTL1
SCHEMBL15910234 0.86 CYP1A2 (0.44) CYP2A6CYP1A2TSHRALDH1A1L3MBTL1
SCHEMBL3284757 0.81 CYP1A2 (0.44) CYP2A6CYP1A2TSHRALDH1A1L3MBTL1
SCHEMBL14003989 0.80 CYP1A2 (0.41) CYP2A6CYP1A2TSHRALDH1A1L3MBTL1
SCHEMBL36539 0.80 CYP1A2 (0.42) CYP2A6CYP1A2TSHRALDH1A1L3MBTL1
SCHEMBL29360067 0.80 CYP1A2 (0.42) CYP2A6CYP1A2TSHRALDH1A1L3MBTL1
SCHEMBL16437959 0.79 CYP1A2 (0.38) CYP2A6CYP1A2TSHRALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2469341-B1 Image bearing member and image forming method, image forming apparatus, and process cartridge RICOH CO LTD (JP) 2016-03-30 EP disclosed
US-8652717-B2 Image bearing member and image forming method, image forming apparatus, and process cartridge using the same RICOH COMPANY, LTD. (JP) 2014-02-18 US disclosed
US-8652717-B2 Image bearing member and image forming method, image forming apparatus, and process cartridge using the same RICOH COMPANY, LTD. (JP) 2014-02-18 US disclosed
US-20120163860-A1 IMAGE BEARING MEMBER AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2012-06-28 US disclosed
US-20120163860-A1 IMAGE BEARING MEMBER AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2012-06-28 US disclosed
EP-2469341-A1 Image bearing member and image forming method, image forming apparatus, and process cartridge Ricoh Company, Ltd. (JP) 2012-06-27 EP disclosed