SCHEMBL10053557

SCHEMBL10053557

CN=Nc1c(O)c(C(=O)Nc2cccc(C)c2)cc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NQO2 P16083 1/20 0.54
▸ MEN1 O00255 8/20 0.52
▸ KMT2A Q03164 8/20 0.52
▸ GAA P10253 2/20 0.52
▸ NPC1 O15118 5/20 0.51
▸ RAB9A P51151 5/20 0.51
▸ MAOB P27338 3/20 0.51
▸ ADORA3 P0DMS8 1/20 0.51
▸ MAOA P21397 1/20 0.51
▸ ALDH1A1 P00352 1/20 0.50
▸ AKR1C3 P42330 1/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ PLA2G7 Q13093 1/20 0.47
▸ F12 P00748 1/20 0.46
▸ MAPT P10636 2/20 0.46
▸ LMNA P02545 1/20 0.46
▸ TP53 P04637 1/20 0.46
▸ PKM P14618 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12799094 0.89 NQO2 (0.65) NQO2MEN1KMT2AGAANPC1
SCHEMBL14445599 0.83 MEN1 (0.58) MEN1KMT2AGAANPC1RAB9A
SCHEMBL17804090 0.83 STAT3 (0.52) NQO2MEN1KMT2AGAANPC1
SCHEMBL13244376 0.82 NQO2 (0.53) NQO2MEN1KMT2AGAANPC1
SCHEMBL13863125 0.81 NQO2 (0.73) NQO2MEN1KMT2AGAANPC1
SCHEMBL14010985 0.80 MEN1 (0.55) MEN1KMT2AGAANPC1RAB9A
SCHEMBL1087081 0.80 NQO2 (0.47) NQO2MEN1KMT2AGAANPC1
SCHEMBL1084913 0.80 NQO2 (0.47) NQO2MEN1KMT2AGAANPC1
SCHEMBL20328905 0.80 KCNK3 (0.48) NQO2MEN1KMT2AGAANPC1
SCHEMBL9892958 0.79 NQO2 (0.52) NQO2MEN1KMT2AGAANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8652717-B2 Image bearing member and image forming method, image forming apparatus, and process cartridge using the same RICOH COMPANY, LTD. (JP) 2014-02-18 — — US disclosed
US-8247143-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2012-08-21 — — US disclosed
US-20120163860-A1 IMAGE BEARING MEMBER AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2012-06-28 — — US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 — — US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 — — US disclosed
US-7897309-B2 Bisazo compound, 2-hydroxy-3-phenylcarbamoyl naphthalene compound and method manufacturing bisazo compound RICOH COMPANY, LTD. (JP) 2011-03-01 — — US disclosed
US-7858278-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY LIMITED (JP) 2010-12-28 — — US disclosed
US-7858278-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY LIMITED (JP) 2010-12-28 — — US disclosed
US-7781134-B2 Electrophotographic photoreceptor, image forming method, image forming apparatus and process cartridge for the image forming apparatus RICOH COMPANY, LTD. (JP) 2010-08-24 — — US disclosed
US-20100119260-A1 PHOTORECEPTOR, IMAGE FORMATION METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2010-05-13 — — US disclosed
US-7691931-B2 Organic-inorganic hybrid material and method of preparing the organic-inorganic hybrid material, and electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method using the organic-inorganic hybrid material RICOH COMPANY LTD. (JP) 2010-04-06 — — US disclosed
US-20080096117-A1 Bisazo compound, 2-hydroxy-3-phenylcarbamoyl naphthalene compound and method manufacturing bisazo compound RICOH COMPANY, LTD. 2008-04-24 — — US disclosed
US-7341814-B2 Electrophotographic photoconductor, preparation method thereof, electrophotographic apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2008-03-11 — — US disclosed
US-7341814-B2 Electrophotographic photoconductor, preparation method thereof, electrophotographic apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2008-03-11 — — US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 — — US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 — — US disclosed
US-20070269729-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-11-22 — — US disclosed
US-20070269729-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-11-22 — — US disclosed
US-7194224-B2 Image forming apparatus, image forming process, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-20 — — US disclosed
US-7194224-B2 Image forming apparatus, image forming process, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080096117-A1 Bisazo compound, 2-hydroxy-3-phenylcarbamoyl naphthalene compound and method manufacturing bisazo compound AHR, PBRM1, AR NQO2 604/4885MEN1 1766/4885KMT2A 663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback