SCHEMBL1005357

SCHEMBL1005357

OCCC(O)OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.67
CCNB1 P14635 1/20 0.67
CA2 P00918 2/20 0.45
CA9 Q16790 1/20 0.45
LDHA P00338 1/20 0.40
EPHX2 P34913 3/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ADORA1 P30542 1/20 0.37
PPARG P37231 2/20 0.32
PPARD Q03181 2/20 0.32
PPARA Q07869 2/20 0.32
GAA P10253 1/20 0.32
TYR P14679 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20746468 0.90 CDK1 (0.66) CDK1CCNB1CA2CA9LDHA
SCHEMBL6700763 0.89 CDK1 (0.65) CDK1CCNB1CA2CA9LDHA
SCHEMBL3400018 0.88 CDK1 (0.64) CDK1CCNB1CA2CA9LDHA
SCHEMBL26185797 0.87 CDK1 (0.69) CDK1CCNB1CA2CA9LDHA
SCHEMBL17165136 0.87 CDK1 (0.69) CDK1CCNB1CA2CA9LDHA
SCHEMBL27667174 0.86 CDK1 (0.70) CDK1CCNB1CA2CA9LDHA
Sucrose SCHEMBL3400014 0.85 CDK1 (0.65) CDK1CCNB1CA2CA9LDHA
SCHEMBL27943621 0.84 CDK1 (0.65) CDK1CCNB1CA2CA9LDHA
SCHEMBL245645 0.84 CDK1 (0.79) CDK1CCNB1CA2CA9LDHA
SCHEMBL8994672 0.84 CDK1 (0.67) CDK1CCNB1CA2CA9LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11987630-B2 Anti-vista antibodies and fragments, uses thereof, and methods of identifying same JANSSEN PHARMACEUTICA NV (BE) 2024-05-21 US disclosed
US-20230374593-A1 PKD MUTATIONS AND EVALUATION OF SAME ATHENA DIAGNOSTICS, INC. (US) 2023-11-23 US disclosed
US-11655508-B2 PKD mutations and evaluation of same ATHENA DIAGNOSTICS, INC. (US) 2023-05-23 US disclosed
US-11339217-B2 Methods and agents for the diagnosis and treatment of hepatocellular carcinoma CIRCULAR COMMITMENT COMPANY (TW) 2022-05-24 US disclosed
US-20210347896-A1 Anti-Vista Antibodies And Fragments, Uses Thereof, And Methods Of Identifying Same JANSSEN PHARMACEUTICA NV (BE) 2021-11-11 US disclosed
US-20210318322-A1 ANTI-VISTA ANTIBODIES AND FRAGMENTS JANSSEN PHARMACEUTICA NV (BE) 2021-10-14 US disclosed
US-20210171640-A1 ANTI-VISTA ANTIBODIES AND FRAGMENTS, USES THEREOF, AND METHODS OF IDENTIFYING SAME JANSSEN PHARMACEUTICA NV 2021-06-10 US disclosed
US-11014987-B2 Anti-vista antibodies and fragments, uses thereof, and methods of identifying same JANSSEN PHARMACEUTICS NV (BE) 2021-05-25 US disclosed
US-11009509-B2 Anti-VISTA antibodies and fragments JANSSEN PHARMACEUTICA NV (BE) 2021-05-18 US disclosed
US-20210079472-A1 PKD MUTATIONS AND EVALUATION OF SAME ATHENA DIAGNOSTICS, INC. (US) 2021-03-18 US disclosed
WO-2001002606-A2 GENETIC TEST TO DETERMINE NON-RESPONSIVENESS TO STATIN DRUG TREATMENT CEDARS-SINAI MEDICAL CENTER (US) 2001-01-11 WO disclosed
WO-2000069257-A2 GENETIC MODIFICATION OF MALE GERM CELLS FOR GENERATION OF TRANSGENIC SPECIES AND GENETIC THERAPIES CEDARS-SINAI MEDICAL CENTER (US) 2000-11-23 WO disclosed
WO-2000058518-A2 GENETIC MARKER TEST FOR LUPUS CEDARS-SINAI MEDICAL CENTER (US) 2000-10-05 WO disclosed
EP-1030929-A1 TRANSFECTION AND TRANSFER OF MALE GERM CELLS FOR GENERATION OF TRANSGENIC SPECIES CEDARS-SINAI MEDICAL CENTER (US) 2000-08-30 EP disclosed
WO-1999025863-A1 TRANSFECTION AND TRANSFER OF MALE GERM CELLS FOR GENERATION OF TRANSGENIC SPECIES CEDARS-SINAI MEDICAL CENTER (US) 1999-05-27 WO disclosed
US-RE34077-E Colloid suspension of water, electrolyte, dextran, dextrose, magnesium and potassium compounds CRYOMEDICAL SCIENCES, INC. (US) 1992-09-22 US disclosed
US-5130230-A A solution of water, electrolytes, buffers, sugars, oncotic agents, sugars and potassium ion with a cardioplegia maintenance solution CRYOMEDICAL SCIENCES, INC. (US) 1992-07-14 US disclosed
EP-0414815-A1 BLOOD SUBSTITUTE CRYOMEDICAL SCIENCES, INC. (US) 1991-03-06 EP disclosed
US-4923442-A AQUEOUS ELECTROLYTE-SUGAR SOLUTION FOR LOW TEMPERATURE SURGERY CRYOMEDICAL SCIENCES INC. (US) 1990-05-08 US disclosed
WO-1989010746-A2 BLOOD SUBSTITUTE CRYOMEDICAL SCIENCES INC. (US) 1989-11-16 WO disclosed