Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ampicillin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | RECQL | P46063 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TEK | Q02763 | 1/20 | 0.58 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | SLC19A2 | O60779 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | RARG | P13631 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ampicillin SCHEMBL11233326 | 0.76 | KDM4E (0.88) | KDM4ERECQLTDP1HPGDPOLB | |
| Ampicillin SCHEMBL28900655 | 0.76 | KDM4E (0.96) | KDM4ERECQLTDP1HPGDPOLB | |
| Ampicillin SCHEMBL13240124 | 0.76 | KDM4E (1.00) | KDM4ERECQLTDP1HPGDPOLB | |
| Ampicillin SCHEMBL9528765 | 0.76 | KDM4E (1.00) | KDM4ERECQLTDP1HPGDPOLB | |
| Ampicillin SCHEMBL11985596 | 0.76 | KDM4E (1.00) | KDM4ERECQLTDP1HPGDPOLB | |
| Ampicillin SCHEMBL24312533 | 0.76 | KDM4E (1.00) | KDM4ERECQLTDP1HPGDPOLB | |
| Ampicillin SCHEMBL13014516 | 0.76 | KDM4E (1.00) | KDM4ERECQLTDP1HPGDPOLB | |
| Ampicillin SCHEMBL15577318 | 0.76 | KDM4E (1.00) | KDM4ERECQLTDP1HPGDPOLB | |
| Ampicillin SCHEMBL22380861 | 0.76 | KDM4E (1.00) | KDM4ERECQLTDP1HPGDPOLB | |
| Ampicillin SCHEMBL2282070 | 0.76 | KDM4E (1.00) | KDM4ERECQLTDP1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119345-A4 | ENCAPSULATION OF SENSITIVE LIQUID COMPONENTS INTO A MATRIX TO OBTAIN DISCRETE SHELF-STABLE PARTICLES | GEN MILLS INC (US) | 2004-06-16 | — | — | EP | claimed |
| US-20020044968-A1 | High amount of plasticizer to facilitate plasticization of the matrix material at low shear and then reduced prior to adding the encapsulant to reduce post extrusion | GENERAL MILLS, INC. | 2002-04-18 | — | — | US | claimed |
| JP-2002511777-A | — | — | 2002-04-16 | — | — | JP | claimed |
| EP-1119345-A1 | ENCAPSULATION OF SENSITIVE LIQUID COMPONENTS INTO A MATRIX TO OBTAIN DISCRETE SHELF-STABLE PARTICLES | GENERAL MILLS, INC. (US) | 2001-08-01 | — | — | EP | claimed |
| WO-2000021504-A1 | ENCAPSULATION OF SENSITIVE LIQUID COMPONENTS INTO A MATRIX TO OBTAIN DISCRETE SHELF-STABLE PARTICLES | GENERAL MILLS, INC. (US) | 2000-04-20 | — | — | WO | claimed |
| EP-0935523-A4 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | GEN MILLS INC (US) | 1999-12-29 | — | — | EP | claimed |
| EP-0935523-A1 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | GENERAL MILLS, INC. (US) | 1999-08-18 | — | — | EP | claimed |
| WO-1998018610-A1 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | LENGERICH BERNHARD H VAN (US) | 1998-05-07 | — | — | WO | claimed |
| US-20230218874-A1 | SWAB DELIVERY SYSTEM | ANERGENT PHARMACEUTICALS, INC. (US) | 2023-07-13 | — | — | US | disclosed |
| US-11623075-B2 | Buccal swab delivery system | ANERGENT PHARMACEUTICALS, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-11607392-B2 | Encapsulation system for prolonged release of active agents | TREND INNOVATIONS (CA) | 2023-03-21 | — | — | US | disclosed |
| US-20200376241-A1 | BUCCAL SWAB DELIVERY SYSTEM | STATIM PHARMACEUTICALS, INC. (US) | 2020-12-03 | — | — | US | disclosed |
| US-20200297648-A1 | ENCAPSULATION SYSTEM FOR PROLONGED RELEASE OF ACTIVE AGENTS | TREND INNOVATIONS (CA) | 2020-09-24 | — | — | US | disclosed |
| US-10743604-B2 | Articles of manufacture releasing an active ingredient | NNTT TECH INC. (CA) | 2020-08-18 | — | — | US | disclosed |
| EP-1065936-A1 | ENCAPSULATION OF COMPONENTS INTO EDIBLE PRODUCTS | GENERAL MILLS, INC. (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-2000021504-A1 | ENCAPSULATION OF SENSITIVE LIQUID COMPONENTS INTO A MATRIX TO OBTAIN DISCRETE SHELF-STABLE PARTICLES | GENERAL MILLS, INC. (US) | 2000-04-20 | — | — | WO | disclosed |
| EP-0935523-A4 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | GEN MILLS INC (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1999048372-A1 | ENCAPSULATION OF COMPONENTS INTO EDIBLE PRODUCTS | GENERAL MILLS, INC. (US) | 1999-09-30 | — | — | WO | disclosed |
| EP-0935523-A1 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | GENERAL MILLS, INC. (US) | 1999-08-18 | — | — | EP | disclosed |
| WO-1998018610-A1 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | LENGERICH BERNHARD H VAN (US) | 1998-05-07 | — | — | WO | disclosed |