SCHEMBL10054178

SCHEMBL10054178

O=CC1C2C=CC(C2)C1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 5/20 0.46
TDP1 Q9NUW8 3/20 0.46
APEX1 P27695 1/20 0.46
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 1/20 0.39
CYP2C19 P33261 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
CASP6 P55212 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14549312 0.83 POLB (0.64) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL7260431 0.82 POLB (0.35) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL807539 0.82 POLB (0.35) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL7260426 0.82 POLB (0.35) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL23287488 0.79 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL20346210 0.79 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL381246 0.79 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL1462188 0.79 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL24062391 0.79 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2
SCHEMBL713506 0.79 POLB (0.70) POLBTDP1APEX1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180118887-A1 PRECURSOR COMPOSITION, PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING PRECURSOR COMPOSITION, CURED FILM, METHOD FOR PRODUCING CURED FILM, AND SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed
US-8093348-B1 Polyimides derived from novel asymmetric dianhydrides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2012-01-10 US disclosed
EP-0871677-B1 IMPREGNATION, SEALING AND COATING COMPOUNDS ELANTAS GMBH (DE) 2010-02-17 EP disclosed
US-7662454-B2 Laminate hose made of fluorocopolymer ASAHI GLASS COMPANY, LIMITED (JP) 2010-02-16 US disclosed
US-20070265420-A1 FIBER REINFORCED GAS TURBINE ENGINE COMPONENT GENERAL ELECTRIC COMPANY (US) 2007-11-15 US disclosed
US-20070265424-A1 TAILORABLE POLYIMIDE PREPOLYMER BLENDS, CROSSLINKED POLYMIDES AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY 2007-11-15 US disclosed
US-20070265422-A1 METHOD FOR MAKING COPOLYMERIC POLYIMIDE RESINS GENERAL ELECTRIC COMPANY (US) 2007-11-15 US disclosed
EP-1852743-A1 Method for manufacturing photosensitive resin composition and relief pattern using the same FUJIFILM Corporation (JP) 2007-11-07 EP disclosed
US-4266075-A Bicyclic aldehyde derivatives, their use as perfuming and flavoring ingredients and process for their preparation FIRMENICH, S.A. (CH) 1981-05-05 US disclosed
US-4218347-A Bicyclic aldehyde perfuming and flavoring ingredients FIRMENICH SA (CH) 1980-08-19 US disclosed
US-3992416-A 4-Oxa-5-hydroxypolycycloalkenones-(3) BASF AKTIENGESELLSCHAFT (DT) 1976-11-16 US disclosed