Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.74 |
| ▸ | HMGCR | P04035 | 4/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.74 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | RHOC | P08134 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.54 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.54 |
| ▸ | PDE6D | O43924 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607742 | 1.00 | SLCO1B1 (0.74) | SLCO1B1HMGCRABCB1ABCC2ABCB11 | |
| SCHEMBL15384628 | 0.93 | SLCO1B1 (0.72) | SLCO1B1HMGCRABCB1ABCC2ABCB11 | |
| SCHEMBL10024059 | 0.92 | SLCO1B1 (0.68) | SLCO1B1HMGCRABCB1ABCC2ABCB11 | |
| SCHEMBL12045333 | 0.91 | SLCO1B1 (0.70) | SLCO1B1HMGCRABCB1ABCC2ABCB11 | |
| SCHEMBL12060155 | 0.91 | SLCO1B1 (0.70) | SLCO1B1HMGCRABCB1ABCC2ABCB11 | |
| SCHEMBL14748387 | 0.91 | SLCO1B1 (0.70) | SLCO1B1HMGCRABCB1ABCC2ABCB11 | |
| SCHEMBL5607435 | 0.91 | SLCO1B1 (0.79) | SLCO1B1HMGCRABCB1ABCC2ABCB11 | |
| SCHEMBL14414147 | 0.91 | SLCO1B1 (0.79) | SLCO1B1HMGCRABCB1ABCC2ABCB11 | |
| SCHEMBL14424499 | 0.90 | SLCO1B1 (0.78) | SLCO1B1HMGCRABCB1ABCC2ABCB11 | |
| SCHEMBL14414151 | 0.90 | SLCO1B1 (0.78) | SLCO1B1HMGCRABCB1ABCC2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148550-B2 | selected from fluvastatin, rosuvastatin, cerivastatin, glenvastatin or atorvastatin, by reduction or lactonization of chemical intermediate compounds, then hydrogenation, decyclization and deprotection of hydroxy groups | RATIOPHARM GMBH (DE) | 2012-04-03 | — | — | US | disclosed |
| US-20080249306-A1 | Method for the Production of Statins | RATIOPHARM GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249306-A1 | Method for the Production of Statins | HMGCR, COASY, PCSK9 | SLCO1B1 898/4885HMGCR 1/4885ABCB1 847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.