⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29719532 | 1.00 | — | — | |
| SCHEMBL164659 | 0.79 | TSHR (0.42) | — | |
| SCHEMBL833937 | 0.74 | — | — | |
| Bromide SCHEMBL164660 | 0.72 | TSHR (0.47) | — | |
| Iodide SCHEMBL8772817 | 0.72 | TSHR (0.47) | — | |
| SCHEMBL6178163 | 0.72 | — | — | |
| SCHEMBL1659134 | 0.69 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL5190 | 0.67 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL10593125 | 0.67 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL1155123 | 0.67 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10343998-B2 | Synthetic path to pharmaceutically acceptable Vismodegib | AZAD PHARMACEUTICAL INGREDIENTS AG (CH) | 2019-07-09 | — | — | US | claimed |
| EP-3381900-A1 | NEW SYNTHETIC PATH TO PHARMACEUTICALLY ACCEPTABLE VISMODEGIB | AZAD Pharmaceutical Ingredients AG (CH) | 2018-10-03 | — | — | EP | claimed |
| US-20180273477-A1 | Synthetic Path To Pharmaceutically Acceptable Vismodegib | AZAD PHARMACEUTICAL INGREDIENTS AG (CH) | 2018-09-27 | — | — | US | claimed |
| CN-102066002-B | Original position olefin polymerization catalyst system | PROMERUS, LLC (US) | 2015-08-26 | — | — | CN | claimed |
| CN-102066002-A | In situ olefin polymerization catalyst system | PROMERUS LLC | 2011-05-18 | — | — | CN | claimed |
| EP-1893571-A2 | PROCESS FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES | Microbia Inc. (US) | 2008-03-05 | — | — | EP | claimed |
| WO-2006122020-A2 | PROCESS FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2006-11-16 | — | — | WO | claimed |
| EP-1120397-A2 | Process for preparing triazole derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-08-01 | — | — | EP | claimed |
| EP-0704419-A1 | PROCESS FOR PRODUCING TRIAZOLE DERIVATIVE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-03 | — | — | EP | claimed |
| US-12479873-B2 | Metal complexes | UDC Ireland (IE) | 2025-11-25 | — | — | US | disclosed |
| EP-4333985-B1 | MODULATORS OF TREX1 | CONSTELLATION PHARMACEUTICALS INC (US) | 2025-07-30 | — | — | EP | disclosed |
| WO-2025096957-A1 | RAS-PI3K INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| US-20240262814-A1 | MODULATORS OF TREX1 | CONSTELLATION PHARMACEUTICALS, INC. | 2024-08-08 | — | — | US | disclosed |
| EP-0704419-A1 | PROCESS FOR PRODUCING TRIAZOLE DERIVATIVE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-03 | — | — | EP | disclosed |
| WO-1996002541-A1 | 8-ARYL-1,6-NAPHTHYRIDIN-5-ONES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-02-01 | — | — | WO | disclosed |
| EP-0687678-A1 | Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-12-20 | — | — | EP | disclosed |
| US-5466697-A | 8-phenyl-1,6-naphthyridin-5-ones | SYNTEX (U.S.A.) INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-4902702-A | PREVENTION AND TREATMENT OF PLANT DISEASES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-02-20 | — | — | US | disclosed |
| US-3954753-A | SEDATIVES, MUSCLE RELAXANTS, ANTICONVULSANTS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-04 | — | — | US | disclosed |