⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2254540 | 1.00 | — | — | |
| SCHEMBL1005739 | 1.00 | — | — | |
| SCHEMBL31449842 | 0.75 | — | — | |
| SCHEMBL11298691 | 0.75 | — | — | |
| SCHEMBL2991560 | 0.75 | — | — | |
| SCHEMBL12193974 | 0.75 | — | — | |
| SCHEMBL9022856 | 0.75 | — | — | |
| SCHEMBL2375313 | 0.75 | — | — | |
| SCHEMBL1435402 | 0.75 | — | — | |
| SCHEMBL27692964 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207835-A1 | Alpha, Beta, Unsaturated Nitriles as Fragrances | GIVAUDAN SA (CH) | 2011-08-25 | — | — | US | claimed |
| EP-2079436-B1 | ALPHA, BETA, UNSATURATED NITRILES AS FRAGRANCES | GIVAUDAN SA (CH) | 2010-11-10 | — | — | EP | claimed |
| EP-2079436-A1 | ALPHA, BETA, UNSATURATED NITRILES AS FRAGRANCES | Givaudan SA (CH) | 2009-07-22 | — | — | EP | claimed |
| WO-2008037105-A1 | ALPHA, BETA, UNSATURATED NITRILES AS FRAGRANCES | GIVAUDAN SA (CH) | 2008-04-03 | — | — | WO | claimed |
| US-4320071-A | CATALYTIC DISPROPORTIONATION | PHILLIPS PETROLEUM COMPANY (US) | 1982-03-16 | — | — | US | claimed |
| US-20250197402-A1 | Tyrosine Kinase Inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2025-06-19 | — | — | US | disclosed |
| US-20230151012-A1 | TYROSINE KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2023-05-18 | — | — | US | disclosed |
| US-11365196-B2 | FGFR inhibitor and application thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2022-06-21 | — | — | US | disclosed |
| EP-2758051-B1 | CYANOMETHYLPYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-04-11 | — | — | EP | disclosed |
| EP-2758377-B1 | CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2017-08-02 | — | — | EP | disclosed |
| EP-2758377-B1 | CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2017-08-02 | — | — | EP | disclosed |
| US-9493441-B2 | Acyclic cyanoethylpyrazoles as janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-11-15 | — | — | US | disclosed |
| CN-1281159-A | Protective layer for image recording material | EASTMAN KODAK CO (US) | 2001-01-24 | — | — | CN | disclosed |
| CN-1281162-A | Protective film material of photographic recording material protective layer | EASTMAN KODAK CO (US) | 2001-01-24 | — | — | CN | disclosed |
| US-5498725-A | Process for preparing 5-aminodihydropyrrole intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0663394-A1 | Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-07-19 | — | — | EP | disclosed |
| US-4432991-A | ANALGESICS, FUNGICIDE, BACTERICIDE, ANTIINFLAMMATORY, OR ANTIARTHRITIC AGENTS, ANTIALLERGENS, AND BRONCHODILATOR | AMERICAN CYANAMID COMPANY (US) | 1984-02-21 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4360680-A | ANALGESIC, ANTIINFLAMMATORY AGENT, FUNGICIDE AND BACTERICIDE | AMERICAN CYANAMID COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| US-4320071-A | CATALYTIC DISPROPORTIONATION | PHILLIPS PETROLEUM COMPANY (US) | 1982-03-16 | — | — | US | disclosed |