Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060021 | 0.89 | BRD4 (0.30) | — | |
| SCHEMBL15158884 | 0.89 | — | — | |
| SCHEMBL10060011 | 0.88 | FFAR1 (0.32) | — | |
| SCHEMBL10060024 | 0.85 | FFAR1 (0.31) | — | |
| SCHEMBL10060023 | 0.84 | PDE4A (0.32) | — | |
| SCHEMBL10060009 | 0.83 | FFAR1 (0.35) | — | |
| SCHEMBL1688287 | 0.82 | FFAR1 (0.31) | — | |
| SCHEMBL10060010 | 0.82 | ALOX5AP (0.30) | — | |
| SCHEMBL1688247 | 0.82 | CDK8 (0.30) | CDK8 | |
| SCHEMBL16997145 | 0.81 | FFAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046869-A1 | CYCLIC AMIDE DERIVATIVE | 持田製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |