Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.54 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.54 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27546870 | 0.97 | USP2 (0.59) | USP2HTTLPAR1LPAR3P2RY10 | |
| SCHEMBL903039 | 0.95 | USP2 (0.54) | USP2HTTLPAR1LPAR3 | |
| SCHEMBL899536 | 0.95 | USP2 (0.54) | USP2HTTLPAR1LPAR3 | |
| SCHEMBL17743870 | 0.95 | USP2 (0.54) | USP2HTTLPAR1LPAR3 | |
| SCHEMBL903074 | 0.95 | USP2 (0.54) | USP2HTTLPAR1LPAR3 | |
| SCHEMBL17744012 | 0.95 | USP2 (0.54) | USP2HTTLPAR1LPAR3 | |
| SCHEMBL17147623 | 0.95 | USP2 (0.54) | USP2HTTLPAR1LPAR3 | |
| SCHEMBL17743867 | 0.95 | USP2 (0.54) | USP2HTTLPAR1LPAR3 | |
| SCHEMBL15315277 | 0.95 | USP2 (0.54) | USP2HTTLPAR1LPAR3 | |
| SCHEMBL17744011 | 0.95 | USP2 (0.54) | USP2HTTLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044638-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |