Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.55 |
| ▸ | F3 | P13726 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | MIF | P14174 | 6/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608180 | 1.00 | CYP2C9 (0.63) | CYP2C9CYP1A2CYP3A4HSD11B1F3 | |
| SCHEMBL10061349 | 0.92 | CYP2C9 (0.65) | CYP2C9CYP1A2CYP3A4HSD11B1F3 | |
| SCHEMBL13341570 | 0.83 | CYP1A2 (0.60) | CYP2C9CYP1A2CYP3A4HSD11B1F3 | |
| SCHEMBL10061358 | 0.82 | CYP2C9 (0.48) | CYP2C9CYP1A2CYP3A4HSD11B1F3 | |
| SCHEMBL10061376 | 0.80 | CYP2C9 (0.50) | CYP2C9CYP1A2CYP3A4HSD11B1F3 | |
| SCHEMBL5585355 | 0.79 | CYP1A2 (1.00) | CYP2C9CYP1A2CYP3A4HSD11B1F3 | |
| SCHEMBL14473242 | 0.79 | CYP1A2 (1.00) | CYP2C9CYP1A2CYP3A4HSD11B1F3 | |
| SCHEMBL5585354 | 0.79 | CYP1A2 (1.00) | CYP2C9CYP1A2CYP3A4HSD11B1F3 | |
| SCHEMBL5585181 | 0.72 | CYP2C9 (1.00) | CYP2C9CYP1A2CYP3A4HSD11B1F3 | |
| SCHEMBL5585182 | 0.72 | CYP2C9 (1.00) | CYP2C9CYP1A2CYP3A4HSD11B1F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2010068935-A2 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | CYP2C9 4875/4885CYP1A2 4526/4885CYP3A4 4713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.