SCHEMBL10061599

SCHEMBL10061599

CCCNS(=O)(=O)C(F)(F)C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.53
CA1 P00915 13/20 0.48
PPARA Q07869 3/20 0.39
CA2 P00918 12/20 0.35
MMP1 P03956 3/20 0.35
MMP2 P08253 3/20 0.35
MMP9 P14780 3/20 0.35
MMP8 P22894 3/20 0.35
MMP13 P45452 3/20 0.35
CA12 O43570 2/20 0.34
CA7 P43166 2/20 0.34
CA14 Q9ULX7 1/20 0.34
CA9 Q16790 1/20 0.33
CA13 Q8N1Q1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10063058 0.87 EPHX1 (0.46) EPHX1CA1PPARACA2MMP1
SCHEMBL19042170 0.87 EPHX1 (0.66) EPHX1CA1PPARACA2CA12
SCHEMBL7023194 0.86 EPHX1 (0.69) EPHX1CA1PPARACA2CA12
SCHEMBL19042171 0.85 EPHX1 (0.75) EPHX1CA1PPARACA2CA12
SCHEMBL5955600 0.85 CA1 (0.51) EPHX1CA1CA2MMP1MMP2
SCHEMBL4784342 0.84 CA1 (0.52) EPHX1CA1CA2MMP1MMP2
SCHEMBL9157457 0.84 CA1 (0.52) EPHX1CA1CA2MMP1MMP2
SCHEMBL9068698 0.84 CA1 (0.52) EPHX1CA1CA2MMP1MMP2
SCHEMBL9069199 0.84 CA1 (0.52) EPHX1CA1CA2MMP1MMP2
SCHEMBL9069154 0.84 CA1 (0.52) EPHX1CA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170184962-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
US-20170184964-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
US-20170184963-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
EP-2444845-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2012-04-25 EP disclosed
US-20120082936-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2012-04-05 US disclosed
US-20110223537-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND POLYMER JSR CORPORATION (JP) 2011-09-15 US disclosed