Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 8/20 | 0.33 |
| ▸ | HTR2C | P28335 | 8/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10061692 | 0.78 | KDM4E (0.34) | KDM4EALDH1A1 | |
| SCHEMBL10061686 | 0.74 | POLB (0.37) | KDM4EPOLB | |
| SCHEMBL10061668 | 0.74 | FGFR1 (0.40) | HTR2AHTR2CKDM4EPOLBTSHR | |
| SCHEMBL21744416 | 0.71 | CXCR4 (0.47) | CXCR4HTR2AHTR2CPOLBTSHR | |
| SCHEMBL12020800 | 0.68 | HTR2A (0.45) | HTR2AHTR2CKDM4EPOLBTSHR | |
| SCHEMBL15227772 | 0.67 | HTR2A (0.54) | HTR2AHTR2CKDM4EPOLBTSHR | |
| SCHEMBL13708519 | 0.66 | HTR2A (0.45) | HTR2AHTR2CKDM4EPOLBTSHR | |
| SCHEMBL24050230 | 0.65 | HTR2A (0.42) | HTR2AHTR2CKDM4EPOLBTSHR | |
| SCHEMBL12878072 | 0.64 | HTR2A (0.47) | HTR2AHTR2CKDM4EPOLBTSHR | |
| SCHEMBL1197953 | 0.64 | HTR2A (0.42) | HTR2AHTR2CKDM4EPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207179-B2 | Substituted indolines as tyrosine kinase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-26 | — | — | US | disclosed |
| US-20100222331-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222331-A1 | NEW COMPOUNDS | CCNA1, CCNY, MKI67 | CXCR4 78/4885HTR2A 2908/4885HTR2C 3147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.