Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
| ▸ | ATM | Q13315 | 1/20 | 0.76 |
| ▸ | JUN | P05412 | 1/20 | 0.72 |
| ▸ | MME | P08473 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | JAK2 | O60674 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31432815 | 0.87 | MAPT (0.74) | KMT2AMAPTMEN1MAPK1POLB | |
| SCHEMBL6851610 | 0.87 | MAPT (1.00) | KMT2AMAPTMEN1MAPK1POLB | |
| SCHEMBL24510580 | 0.87 | MAPT (1.00) | KMT2AMAPTMEN1MAPK1POLB | |
| SCHEMBL29857079 | 0.87 | MAPT (1.00) | KMT2AMAPTMEN1MAPK1POLB | |
| SCHEMBL6852865 | 0.87 | MAPT (1.00) | KMT2AMAPTMEN1MAPK1POLB | |
| SCHEMBL22550919 | 0.84 | KMT2A (0.78) | KMT2AMAPTMEN1MAPK1POLB | |
| SCHEMBL31432726 | 0.84 | KMT2A (0.78) | KMT2AMAPTMEN1MAPK1POLB | |
| Cyclovalone SCHEMBL554418 | 0.84 | MEN1 (1.00) | KMT2AMAPTMEN1MAPK1POLB | |
| Cyclovalone SCHEMBL1151847 | 0.84 | MEN1 (1.00) | KMT2AMAPTMEN1MAPK1POLB | |
| Cyclovalone SCHEMBL554417 | 0.84 | MEN1 (1.00) | KMT2AMAPTMEN1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021692-A1 | CURCUMIN ANALOGS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-02-16 | — | — | WO | disclosed |