Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106229 | 0.89 | MAPT (0.41) | PTPN1MAPTTSHRPOLBPDE4A | |
| SCHEMBL9109831 | 0.89 | PTPN1 (0.42) | PTPN1MAPTTSHRPOLBTP53 | |
| SCHEMBL9105461 | 0.88 | MAPT (0.40) | PTPN1MAPTTSHRPOLBPDE4A | |
| SCHEMBL9109029 | 0.88 | TSHR (0.36) | PTPN1MAPTTSHRPOLBPDE4A | |
| SCHEMBL9105480 | 0.88 | PTPN1 (0.38) | PTPN1MAPTTSHRPOLBPDE4A | |
| SCHEMBL9109162 | 0.88 | PTPN1 (0.36) | PTPN1MAPTTSHRPOLBPDE4A | |
| SCHEMBL9104028 | 0.86 | S1PR3 (0.38) | PTPN1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL9110851 | 0.86 | MAPT (0.39) | PTPN1MAPTPDE4APDE4BPDE4D | |
| SCHEMBL9105460 | 0.86 | MAPT (0.36) | PTPN1MAPTTSHRPOLBTP53 | |
| SCHEMBL10032054 | 0.85 | MDM2 (0.35) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142736-A1 | NOVEL PYRIDINE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142736-A1 | NOVEL PYRIDINE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | S1PR1, S1PR3, S1PR2 | PTPN1 706/4885MAPT 2922/4885TSHR 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.