Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12463906 | 0.96 | NPC1 (0.49) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL15932966 | 0.96 | NPC1 (0.49) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL10030281 | 0.96 | NPC1 (0.49) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL10025072 | 0.96 | NPC1 (0.45) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL14421288 | 0.91 | NPC1 (0.45) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL14364546 | 0.91 | POLB (0.47) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL14364648 | 0.90 | NPC1 (0.54) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL19322781 | 0.89 | NPC1 (0.46) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL12608146 | 0.89 | NPC1 (0.45) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL12646212 | 0.89 | NPC1 (0.53) | NPC1RAB9AMAPTPOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178590-B2 | Block copolymer and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20070281195-A1 | Block copolymer and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-12-06 | — | — | US | disclosed |