Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404950 | 0.81 | SLC6A4 (0.63) | CSNK2A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2369166 | 0.81 | CSNK2A1 (1.00) | CSNK2A1 | |
| SCHEMBL12875503 | 0.79 | SLC6A4 (0.50) | CSNK2A1SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL1164547 | 0.76 | EPHX2 (0.49) | CSNK2A1SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL1164545 | 0.76 | EPHX2 (0.49) | CSNK2A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL12875726 | 0.74 | SLC6A4 (0.45) | CSNK2A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5453058 | 0.74 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5453061 | 0.74 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14410831 | 0.74 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17071876 | 0.72 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041158-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-04-05 | — | — | WO | disclosed |