Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.74 |
| ▸ | SMO | Q99835 | 16/20 | 0.74 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3770846 | 0.92 | MAPK14 (0.72) | MAPK14SMO | |
| SCHEMBL3649098 | 0.92 | SMO (0.66) | MAPK14SMOPARP10 | |
| SCHEMBL3649540 | 0.91 | SMO (0.77) | MAPK14SMO | |
| Hydrochloric Acid SCHEMBL3648183 | 0.91 | MAPK14 (0.71) | MAPK14SMO | |
| SCHEMBL3648255 | 0.89 | SMO (0.74) | MAPK14SMO | |
| SCHEMBL3646138 | 0.88 | SMO (0.76) | MAPK14SMO | |
| SCHEMBL3646122 | 0.88 | SMO (0.72) | MAPK14SMO | |
| SCHEMBL3763093 | 0.87 | MAPK14 (0.71) | MAPK14SMO | |
| Water SCHEMBL27817953 | 0.86 | SMO (0.75) | MAPK14SMO | |
| SCHEMBL3769398 | 0.86 | MAPK14 (0.89) | MAPK14SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010132-A1 | SUSTAINED-RELEASE COMPOSITION COMPRISING COMPOUND 600 | ASTRAZENECA AB (SE) | 2011-01-27 | — | — | WO | disclosed |