Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597343 | 0.82 | — | — | |
| Propane SCHEMBL28273128 | 0.79 | CYP2D6 (0.52) | DPP4DPP8DPP9SMYD3CYP1A2 | |
| SCHEMBL26575461 | 0.79 | CTSC (0.37) | CYP1A2CYP2D6ALOX15CYP2C19SLC1A3 | |
| SCHEMBL19374366 | 0.79 | CTSC (0.37) | CYP1A2CYP2D6ALOX15CYP2C19SLC1A3 | |
| SCHEMBL13188074 | 0.79 | CTSC (0.37) | CYP1A2CYP2D6ALOX15CYP2C19SLC1A3 | |
| SCHEMBL16083485 | 0.78 | DPP8 (0.41) | DPP4DPP8DPP9CYP1A2CYP2D6 | |
| Propane SCHEMBL28234826 | 0.78 | SMYD3 (0.40) | DPP4DPP8DPP9SMYD3CYP1A2 | |
| SCHEMBL12281477 | 0.78 | CTSC (0.41) | SMYD3CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL8916458 | 0.78 | CTSC (0.41) | SMYD3CYP1A2CYP2D6ALOX15CYP2C19 | |
| Alcohol SCHEMBL28063732 | 0.78 | CYP2D6 (0.50) | DPP4DPP8DPP9SMYD3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | LSS, ABCG2, SELL | DPP4 3178/4885DPP8 2940/4885DPP9 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.