SCHEMBL10067945

SCHEMBL10067945

CCC(=O)[C@H]1CCCCN1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRCP P42785 3/20 0.44
DPP7 Q9UHL4 1/20 0.39
SCN4A P35499 1/20 0.38
FDPS P14324 1/20 0.38
NOS2 P35228 2/20 0.38
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
DPP4 P27487 2/20 0.36
DPP8 Q6V1X1 1/20 0.35
DPP9 Q86TI2 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8285912 1.00 PRCP (0.44) PRCPDPP7SCN4AFDPSNOS2
SCHEMBL10067946 1.00 PRCP (0.44) PRCPDPP7SCN4AFDPSNOS2
SCHEMBL3957134 1.00 PRCP (0.44) PRCPDPP7SCN4AFDPSNOS2
SCHEMBL31048387 0.98 PRCP (0.42) PRCPDPP7SCN4AFDPSNOS2
SCHEMBL7299775 0.98 PRCP (0.42) PRCPDPP7SCN4AFDPSNOS2
SCHEMBL7298202 0.98 PRCP (0.42) PRCPDPP7SCN4AFDPSNOS2
SCHEMBL14296418 0.94
SCHEMBL878969 0.94
SCHEMBL805298 0.94
SCHEMBL15808359 0.84 PRCP (0.45) PRCPDPP7SCN4AFDPSNOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348518-A1 HELICASE INHIBITORS FOR TREATMENT OF MEDICAL DISORDERS H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 2023-11-02 US disclosed
US-20120077711-A1 Novel Ligands and Libraries of Ligands SUNESIS PHARMACEUTICALS, INC. (US) 2012-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348518-A1 HELICASE INHIBITORS FOR TREATMENT OF MEDICAL DISORDERS RECQL, DDX21, DDX41 PRCP 2978/4885DPP7 2788/4885SCN4A 3606/4885
US-20120077711-A1 Novel Ligands and Libraries of Ligands LSS, ABCG2, SELL PRCP 1915/4885DPP7 2709/4885SCN4A 1985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.