Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10038024 | 1.00 | GABRR1 (0.39) | GABRR1GRM2GABRR2GAAHPSE | |
| SCHEMBL3922207 | 1.00 | GABRR1 (0.39) | GABRR1GRM2GABRR2GAAHPSE | |
| SCHEMBL10589514 | 1.00 | GABRR1 (0.39) | GABRR1GRM2GABRR2GAAHPSE | |
| SCHEMBL27283686 | 0.81 | — | — | |
| SCHEMBL10536736 | 0.80 | GABRR1 (0.42) | GABRR1GRM2GABRR2MEN1KMT2A | |
| SCHEMBL3627087 | 0.80 | GABRR1 (0.42) | GABRR1GRM2GABRR2MEN1KMT2A | |
| SCHEMBL4419497 | 0.80 | GABRR1 (0.42) | GABRR1GRM2GABRR2MEN1KMT2A | |
| SCHEMBL4419500 | 0.80 | GABRR1 (0.42) | GABRR1GRM2GABRR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11127916 | 0.78 | GABRR1 (0.40) | GABRR1GRM2GABRR2MEN1KMT2A | |
| SCHEMBL9792348 | 0.76 | GABRR1 (0.39) | GABRR1GRM2GABRR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9592497-B2 | Process for the asymmetric hydrogenation of imides | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2017-03-14 | — | — | US | disclosed |
| US-20120165546-A1 | PROCESS FOR THE ASYMMETRIC HYDROGENATION OF IMIDES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165546-A1 | PROCESS FOR THE ASYMMETRIC HYDROGENATION OF IMIDES | IDH2, HRH4, HPSE | GABRR1 1675/4885GRM2 437/4885GABRR2 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.