SCHEMBL10068290

SCHEMBL10068290

CCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(=O)C[C@@H]21

nearest known ligand 0.78

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 12/20 0.69
▸ NR1I2 O75469 1/20 0.64
▸ ADORA3 P0DMS8 1/20 0.64
▸ CNR1 P21554 1/20 0.64
▸ SLC6A3 Q01959 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16922165 0.88 CNR2 (0.72) CNR2NR1I2ADORA3CNR1SLC6A3
SCHEMBL15558108 0.88 CNR2 (0.72) CNR2NR1I2ADORA3CNR1SLC6A3
SCHEMBL31545381 0.88 CNR2 (0.72) CNR2NR1I2ADORA3CNR1SLC6A3
SCHEMBL11455743 0.88 CNR2 (0.72) CNR2NR1I2ADORA3CNR1SLC6A3
SCHEMBL7755404 0.88 CNR2 (0.72) CNR2NR1I2ADORA3CNR1SLC6A3
SCHEMBL11541884 0.88 CNR2 (0.72) CNR2NR1I2ADORA3CNR1SLC6A3
SCHEMBL17686850 0.88 CNR2 (0.71) CNR2NR1I2ADORA3CNR1SLC6A3
SCHEMBL11444967 0.87 CNR2 (0.71) CNR2NR1I2ADORA3CNR1SLC6A3
SCHEMBL11787625 0.87 CNR2 (0.71) CNR2NR1I2ADORA3CNR1SLC6A3
SCHEMBL11612711 0.87 CNR2 (0.71) CNR2NR1I2ADORA3CNR1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9347961-B2 Test kit for the quantitative determination of narcotic drugs CHIRON AS (NO) 2016-05-24 — — US disclosed
US-9155797-B2 Oligomer-cannabinoid conjugates NEKTAR THERAPEUTICS (US) 2015-10-13 — — US disclosed
US-20150204893-A1 TEST KIT FOR THE QUANTITATIVE DETERMINATION OF NARCOTIC DRUGS CHIRON AS (NO) 2015-07-23 — — US disclosed
US-20140329895-A1 OLIGOMER-CANNABINOID CONJUGATES NEKTAR THERAPEUTICS 2014-11-06 — — US disclosed
US-8829043-B2 Oligome-cannabinoid conjugates NEKTAR THERAPEUTICS (US) 2014-09-09 — — US disclosed
US-20120022063-A1 Oligomer-Cannabinoid Conjugates NEKTAR THERAPEUTICS (US) 2012-01-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140329895-A1 OLIGOMER-CANNABINOID CONJUGATES CNR2, CNR1, OPRL1 CNR2 1/4885NR1I2 1714/4885ADORA3 461/4885
US-20120022063-A1 Oligomer-Cannabinoid Conjugates CNR2, CNR1, OPRL1 CNR2 1/4885NR1I2 1714/4885ADORA3 461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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