Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14709673 | 0.94 | HPGD (0.47) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL31231172 | 0.94 | HPGD (0.47) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL22625915 | 0.91 | HPGD (0.49) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL225098 | 0.91 | USP2 (0.51) | HPGDUSP2SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL2673847 | 0.83 | HPGD (0.51) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL6943029 | 0.82 | HPGD (0.43) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL20482260 | 0.82 | HPGD (0.43) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL2279068 | 0.82 | HPGD (0.43) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL31693670 | 0.82 | USP2 (0.46) | HPGDUSP2SMN1; SMN2EPHX2TSHR | |
| SCHEMBL17469418 | 0.81 | USP2 (0.45) | HPGDUSP2SMN1; SMN2EPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | LSS, ABCG2, SELL | HPGD 2879/4885USP2 4759/4885SMN1; SMN2 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.