Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069048 | 0.81 | MRGPRX4 (0.44) | MRGPRX4AURKARPS6KB1LMNAMEN1 | |
| SCHEMBL10069050 | 0.80 | AURKA (0.40) | MRGPRX4AURKARPS6KB1LMNAMEN1 | |
| SCHEMBL10069061 | 0.72 | KMT2A (0.56) | MRGPRX4LMNAMEN1KMT2AMAPT | |
| SCHEMBL10068778 | 0.71 | HPGD (0.43) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL10068802 | 0.70 | KLKB1 (0.41) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL10069568 | 0.69 | MEN1 (0.48) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL38987 | 0.68 | MAPT (0.59) | LMNAMAPTRAB9AALDH1A1GAA | |
| SCHEMBL2809253 | 0.68 | MAPT (0.59) | LMNAMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL10068957 | 0.66 | HPGD (0.42) | MAPTALDH1A1GAAPLA2G4A | |
| SCHEMBL10068953 | 0.66 | KLKB1 (0.40) | LMNAMEN1KMT2AMAPTREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019428-A1 | BENZOHYDROL DERIVATIVES, A PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |