⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403117 | 0.87 | — | — | |
| SCHEMBL7571723 | 0.69 | — | — | |
| Bromide SCHEMBL7631202 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL21519650 | 0.67 | — | — | |
| SCHEMBL21622177 | 0.66 | MIF (0.32) | — | |
| SCHEMBL8932532 | 0.66 | — | — | |
| SCHEMBL14191783 | 0.65 | — | — | |
| SCHEMBL11731881 | 0.65 | — | — | |
| SCHEMBL12437160 | 0.65 | — | — | |
| SCHEMBL20393678 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840688-B2 | Compositions and methods for inhibiting gene expression of Hif2alpha | Arrowhead Pharmaceuticals, Inc. (US) | 2023-12-12 | — | — | US | disclosed |
| US-11840688-B2 | Compositions and methods for inhibiting gene expression of Hif2alpha | Arrowhead Pharmaceuticals, Inc. (US) | 2023-12-12 | — | — | US | disclosed |
| US-20210180066-A1 | Compositions and Methods for Inhibiting Gene Expression of Hif2alpha | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2021-06-17 | — | — | US | disclosed |
| EP-3030244-B1 | POLYCONJUGATES FOR DELIVERY OF RNAI TRIGGERS TO TUMOR CELLS IN VIVO | ARROWHEAD PHARMACEUTICALS INC (US) | 2021-04-21 | — | — | EP | disclosed |
| US-10927373-B2 | Compositions and methods for inhibiting gene expression of Hif2alpha | Arrowhead Pharmaceuticals, Inc. (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200270207-A1 | DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-08-27 | — | — | US | disclosed |
| US-10544105-B2 | Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-01-28 | — | — | US | disclosed |
| US-20180201586-A1 | DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CONTAINING CYCLOPROPANO LINKAGE | SAI LIFE SCIENCES LIMITED (IN) | 2018-07-19 | — | — | US | disclosed |
| US-9976141-B2 | Compositions and methods for inhibiting gene expression of Hif2alpha | Arrowhead Pharmaceuticals, Inc. (US) | 2018-05-22 | — | — | US | disclosed |
| US-9976141-B2 | Compositions and methods for inhibiting gene expression of Hif2alpha | Arrowhead Pharmaceuticals, Inc. (US) | 2018-05-22 | — | — | US | disclosed |
| US-20130158203-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | CARNEGIE MELLON UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130158203-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | CARNEGIE MELLON UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130158203-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | CARNEGIE MELLON UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| EP-1864976-B1 | PROPANE-1,3-DION DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-10-10 | — | — | EP | disclosed |
| WO-2012018650-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-09 | — | — | WO | disclosed |
| US-7960562-B2 | Propane-1,3-dione derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-06-14 | — | — | US | disclosed |
| US-7960562-B2 | Propane-1,3-dione derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090181964-A1 | Propane-1,3-Dione Derivative or Salt Thereof | ASTELLAS PHARMA INC. | 2009-07-16 | — | — | US | disclosed |
| US-20090181964-A1 | Propane-1,3-Dione Derivative or Salt Thereof | ASTELLAS PHARMA INC. | 2009-07-16 | — | — | US | disclosed |
| EP-1864976-A1 | PROPANE-1,3-DION DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2007-12-12 | — | — | EP | disclosed |