Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.47 |
| ▸ | CCR5 | P51681 | 2/20 | 0.47 |
| ▸ | CCR8 | P51685 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17367800 | 0.98 | KDM4E (0.51) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL17945610 | 0.97 | MEN1 (0.54) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL17343370 | 0.95 | KDM4E (0.47) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL19009531 | 0.95 | MEN1 (0.51) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL18327439 | 0.95 | KDM4E (0.53) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL17945817 | 0.93 | MEN1 (0.54) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL16305245 | 0.93 | KDM4E (0.46) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL21018792 | 0.93 | KDM4E (0.49) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL17367802 | 0.93 | KDM4E (0.51) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL16305222 | 0.92 | MEN1 (0.49) | KDM4ELMNAALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130256646-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130256646-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| WO-2012088192-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |