Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17299276 | 1.00 | ESR1 (0.39) | ESR1ESR2ACHE | |
| SCHEMBL15045291 | 1.00 | ESR1 (0.39) | ESR1ESR2ACHE | |
| SCHEMBL17299260 | 1.00 | ESR1 (0.39) | ESR1ESR2ACHE | |
| SCHEMBL13298432 | 0.86 | ESR1 (0.51) | ESR1ESR2ACHE | |
| SCHEMBL17299270 | 0.86 | ESR1 (0.51) | ESR1ESR2ACHE | |
| SCHEMBL17299259 | 0.86 | ESR1 (0.51) | ESR1ESR2ACHE | |
| SCHEMBL17299641 | 0.86 | ESR1 (0.51) | ESR1ESR2ACHE | |
| SCHEMBL17299275 | 0.86 | ESR1 (0.51) | ESR1ESR2ACHE | |
| SCHEMBL15045295 | 0.86 | ESR1 (0.51) | ESR1ESR2ACHE | |
| SCHEMBL13298442 | 0.83 | ESR1 (0.40) | ESR1ESR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106035-B2 | 25-SO2-substituted analogs of 1μ,25-dihydroxyvitamin D3 | CYTOCHROMA INC. (CA) | 2012-01-31 | — | — | US | disclosed |
| US-7166585-B2 | 24-Sulfur-substituted analogs of 1α,25-dihydroxy vitamin D3 | CYTOCHROMA INC. (CA) | 2007-01-23 | — | — | US | disclosed |