Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292156 | 0.91 | KMT2A (0.64) | KMT2AMAPTFFAR3HDAC3HDAC1 | |
| SCHEMBL1873457 | 0.90 | KMT2A (0.70) | KMT2AMAPTFFAR3HDAC3HDAC1 | |
| SCHEMBL9128435 | 0.88 | KMT2A (0.61) | KMT2AMAPTFFAR3HDAC3HDAC1 | |
| SCHEMBL10414974 | 0.88 | KMT2A (0.75) | KMT2AMAPTAKR1B1SLC22A6GPR84 | |
| SCHEMBL12568553 | 0.87 | SLC22A6 (0.69) | KMT2AMAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL10071351 | 0.86 | KMT2A (0.71) | KMT2AMAPTAKR1B1SLC22A6GPR84 | |
| SCHEMBL9292367 | 0.85 | EGLN1 (0.61) | KMT2AMAPTFFAR3HDAC3HDAC1 | |
| SCHEMBL28671271 | 0.85 | KMT2A (0.77) | KMT2AMAPTFFAR3HDAC3HDAC1 | |
| SCHEMBL19171953 | 0.84 | KMT2A (0.83) | KMT2AMAPTAKR1B1SLC22A6GPR84 | |
| SCHEMBL10071357 | 0.84 | KMT2A (0.83) | KMT2AMAPTAKR1B1SLC22A6GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202963-B2 | Tissue adhesives with modified elasticity | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-06-19 | — | — | US | disclosed |
| US-20110269916-A1 | TISSUE ADHESIVES WITH MODIFIED ELASTICITY | ACTAMAX SURGICAL MATERIALS, LLC | 2011-11-03 | — | — | US | disclosed |