Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984457 | 0.84 | TDP1 (0.46) | TDP1HCAR2KEAP1FFAR1ESR1 | |
| SCHEMBL30984441 | 0.84 | TDP1 (0.46) | TDP1HCAR2KEAP1FFAR1ESR1 | |
| SCHEMBL30984460 | 0.84 | TDP1 (0.46) | TDP1HCAR2KEAP1FFAR1ESR1 | |
| SCHEMBL3248092 | 0.82 | FFAR4 (0.55) | TDP1HCAR2KEAP1FFAR1ESR1 | |
| SCHEMBL9956104 | 0.81 | TSHR (0.54) | TDP1NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL3884363 | 0.81 | FFAR4 (0.54) | TDP1HCAR2KEAP1FFAR1ESR1 | |
| Hydrochloric Acid SCHEMBL7690739 | 0.81 | FFAR4 (0.54) | TDP1HCAR2KEAP1FFAR1ESR1 | |
| SCHEMBL8531827 | 0.79 | FFAR4 (0.52) | TDP1HCAR2KEAP1FFAR1ESR1 | |
| SCHEMBL3257614 | 0.79 | TDP1 (0.48) | TDP1HCAR2KEAP1FFAR1ESR1 | |
| SCHEMBL3884361 | 0.79 | FFAR4 (0.52) | TDP1HCAR2KEAP1FFAR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130272978-A1 | DIHYDROXYACETONE MONOETHERS | MERCK PATENT GMBH (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20130272978-A1 | DIHYDROXYACETONE MONOETHERS | MERCK PATENT GMBH (DE) | 2013-10-17 | — | — | US | disclosed |
| WO-2012084121-A1 | DIHYDROXYACETONE MONOETHER | MERCK PATENT GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130272978-A1 | DIHYDROXYACETONE MONOETHERS | GNPAT, UGT1A7, UGT1A3 | TDP1 1476/4885HCAR2 1917/4885KEAP1 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.