Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19605323 | 0.80 | PSEN1 (0.36) | — | |
| SCHEMBL6979164 | 0.78 | — | — | |
| SCHEMBL13762127 | 0.74 | — | — | |
| SCHEMBL2085604 | 0.72 | — | — | |
| SCHEMBL12588569 | 0.70 | EPHX1 (0.48) | EPHX1LMNA | |
| SCHEMBL12522719 | 0.70 | EPHX1 (0.48) | EPHX1LMNA | |
| SCHEMBL13888656 | 0.70 | EPHX1 (0.48) | EPHX1LMNA | |
| SCHEMBL12851325 | 0.70 | — | — | |
| SCHEMBL12522714 | 0.70 | EPHX1 (0.48) | EPHX1LMNA | |
| SCHEMBL19571016 | 0.68 | EPHX1 (0.61) | EPHX1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854800-B1 | Antitumoral derivatives of Ecteinascidin ET-743 | PHARMA MAR SA (ES) | 2012-06-27 | — | — | EP | disclosed |