Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 6/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181642 | 0.80 | CYP19A1 (0.40) | GRM2GRM3 | |
| SCHEMBL181317 | 0.80 | CYP19A1 (0.40) | GRM2GRM3 | |
| SCHEMBL181316 | 0.80 | CYP19A1 (0.40) | GRM2GRM3 | |
| SCHEMBL22413581 | 0.80 | PDE4D (0.36) | PDE4DCTSLPDE4APDE4BPDE4C | |
| SCHEMBL13617237 | 0.76 | PDE4D (0.40) | PDE4DCTSLPDE4APDE4BPDE4C | |
| SCHEMBL6840506 | 0.76 | PDE4D (0.40) | PDE4DCTSLPDE4APDE4BPDE4C | |
| SCHEMBL4666526 | 0.76 | PDE4D (0.36) | PDE4DPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL4665000 | 0.75 | PDE4D (0.36) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL13563616 | 0.74 | PDE4D (0.35) | PDE4DCTSLPDE4APDE4BPDE4C | |
| SCHEMBL23296777 | 0.72 | PDE4D (0.33) | PDE4DCTSLGRM2GRM3PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025701-A1 | ALPHA, ALPHA - DI SUBSTITUTED GLYCINE ESTER DERIVATIVES AND THEIR USE AS HDAC INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2012-03-01 | — | — | WO | disclosed |