Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | UGCG | Q16739 | 2/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14923195 | 0.91 | TSHR (0.57) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL2677431 | 0.90 | — | — | |
| SCHEMBL20102780 | 0.86 | TSHR (0.68) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL13360001 | 0.86 | TSHR (0.68) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL15834831 | 0.86 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL19450572 | 0.86 | TSHR (0.82) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL12914753 | 0.86 | TSHR (0.82) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL19450571 | 0.86 | TSHR (0.82) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL12873237 | 0.85 | TSHR (0.72) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL123896 | 0.84 | TSHR (0.78) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999177-B1 | RADIATION-OR THERMALLY-CURABLE BARRIER SEALANTS | HENKEL AG & CO KGAA (DE) | 2016-05-11 | — | — | EP | disclosed |
| WO-2013090529-A1 | NEAR-INFRARED ABSORBING FILM COMPOSITION FOR LITHOGRAPHIC APPLICATION | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2012003136-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-05 | — | — | WO | disclosed |
| US-20100065871-A1 | POLYMERS WITH TRANSMISSION INTO THE ULTRAVIOLET | UNIVERSITY OF STRATHCLYDE (GB) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100065871-A1 | POLYMERS WITH TRANSMISSION INTO THE ULTRAVIOLET | PUF60, C9, PARG | TSHR 4160/4885SMN1; SMN2 4288/4885ALDH1A1 1029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.