SCHEMBL10073322

SCHEMBL10073322

CCc1ccc(Cc2cc([C@]3(C)OC(CO)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.58
SLC5A1 P13866 14/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19303578 0.91 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL13445693 0.91 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL46287 0.89 SLC5A2 (0.75) SLC5A2SLC5A1
SCHEMBL46238 0.88 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL10073324 0.88 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL27731971 0.87 SLC5A2 (0.57) SLC5A2SLC5A1
SCHEMBL1639078 0.87 SLC5A2 (0.57) SLC5A2SLC5A1
SCHEMBL13707330 0.85 SLC5A2 (0.55) SLC5A2SLC5A1
SCHEMBL14012864 0.85 SLC5A2 (0.55) SLC5A2SLC5A1
SCHEMBL28982 0.82 SLC5A2 (0.58) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012003811-A1 C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD ZHEJIANG BETA PHARMA INC. (CN) 2012-01-12 WO disclosed