Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380707 | 0.91 | ELANE (0.34) | ELANECACNA1HCACNA1GCACNA1ICNR2 | |
| SCHEMBL380708 | 0.91 | ELANE (0.34) | ELANECACNA1HCACNA1GCACNA1ICNR2 | |
| SCHEMBL2318568 | 0.79 | ELANE (0.37) | ELANE | |
| SCHEMBL2318571 | 0.79 | ELANE (0.37) | ELANE | |
| SCHEMBL2212981 | 0.78 | GLA (0.33) | ELANECACNA1HCACNA1GCACNA1I | |
| SCHEMBL2209256 | 0.78 | ELANE (0.41) | ELANE | |
| SCHEMBL2212409 | 0.78 | ELANE (0.41) | ELANE | |
| SCHEMBL2212548 | 0.78 | GLA (0.33) | ELANECACNA1HCACNA1GCACNA1I | |
| SCHEMBL14163211 | 0.78 | SCN2B (0.36) | ELANECNR2 | |
| SCHEMBL2316297 | 0.76 | ELANE (0.36) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086938-B1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2012-01-25 | — | — | EP | disclosed |