⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633090 | 0.78 | — | — | |
| SCHEMBL7877576 | 0.74 | — | — | |
| SCHEMBL2310070 | 0.74 | — | — | |
| SCHEMBL15630607 | 0.74 | — | — | |
| SCHEMBL13180964 | 0.74 | — | — | |
| SCHEMBL7740505 | 0.74 | — | — | |
| SCHEMBL12956814 | 0.70 | HRH3 (0.45) | — | |
| SCHEMBL4681508 | 0.70 | — | — | |
| SCHEMBL7627177 | 0.70 | — | — | |
| SCHEMBL4614442 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247382-A1 | SMALL MOLECULES TARGETING ANDROGEN RECEPTOR NUCLEAR LOCALIZATION AND/OR LEVEL IN PROSTATE CANCER | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-08-31 | — | — | US | disclosed |
| US-8093274-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100063114-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-11 | — | — | US | disclosed |
| WO-2007038169-A2 | MULTI-VALENT GUANIDINIUM COMPOUNDS FOR MOLECULAR TRANSLOCATION ACROSS CELLULAR MEMBRANES AND EPITHELIAL TISSUES | NITTO DENKO CORPORATION (JP) | 2007-04-05 | — | — | WO | disclosed |