SCHEMBL1007397

SCHEMBL1007397

ClCc1c(Cl)cccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.52
AKR1B1 P15121 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2A6 P11509 1/20 0.45
LMNA P02545 2/20 0.44
TSHR P16473 1/20 0.44
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 2/20 0.40
GLA P06280 1/20 0.40
HTT P42858 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CYP2A13 Q16696 1/20 0.40
PNMT P11086 1/20 0.40
DPP4 P27487 1/20 0.39
POLB P06746 1/20 0.39
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
HTR1A P08908 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5042264 0.97 TAAR1 (0.50) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL11029627 0.97 TAAR1 (0.50) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL1539462 0.84 TAAR1 (0.44) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL30776827 0.82 TAAR1 (0.63) TAAR1SMN1; SMN2CYP1A2LMNAGAA
SCHEMBL21768197 0.82 TAAR1 (0.43) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL30831849 0.82 TAAR1 (0.43) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL9861759 0.82 TAAR1 (0.43) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL21768187 0.82 TAAR1 (0.43) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL601569 0.82 TAAR1 (0.63) TAAR1SMN1; SMN2CYP1A2LMNAGAA
SCHEMBL30831843 0.82 TAAR1 (0.43) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 597 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115613059-B Method for preparing 2, 6-dichlorobenzonitrile by indirect electrosynthesis by taking 2, 6-dichlorobenzyl chloride as raw material 浙江工业大学 2025-05-27 CN claimed
CN-116854611-B Method for preparing 2, 6-dichlorobenzonitrile by gas phase ammoxidation method 湖北纽苏莱新材料有限公司 2024-04-23 CN claimed
CN-115613059-A Method for preparing 2, 6-dichlorobenzonitrile by indirect electrosynthesis with 2, 6-dichlorobenzyl chloride as raw material 浙江工业大学 2023-01-17 CN claimed
CN-110540526-B Carane acidyl 1,2, 3-triazole compound and preparation method and application thereof 广西大学 2022-08-30 CN claimed
CN-110483332-B Method for preparing 2, 6-dichlorobenzonitrile by 2, 6-dichlorobenzylamino iodination method 南京工业大学 2022-07-05 CN claimed
CN-109776255-B Method for preparing 2, 6-dichlorobenzylidene dichloride by low-temperature photochlorination method 南京工业大学 2021-12-07 CN claimed
CN-113582807-A Method for synthesizing 2, 6-dichlorobenzyl chloride 江苏超跃化学有限公司 2021-11-02 CN claimed
CN-109336732-B Method for producing 2, 6-dichlorobenzylidene dichloride and co-producing 2, 6-dichlorotoluene 南京工业大学 2021-03-30 CN claimed
CN-111233705-A Method for preparing corresponding benzonitrile by virtue of benzyl chloride derivative ammoxidation method 南京工业大学 2020-06-05 CN claimed
CN-110540526-A Carane acidyl 1,2, 3-triazole compound and preparation method and application thereof UNIV GUANGXI 2019-12-06 CN claimed
EP-3209638-A1 POLYPRENYLATED PHLOROGLUCINOL COMPOUNDS AS POTENT P-GLYCOPROTEIN INDUCERS Council of Scientific and Industrial Research (IN) 2017-08-30 EP claimed
CN-102399192-A Method for preparing isoconazole nitrate BEIJING HAIYAN PHARMACEUTICAL CO LTD OF YANGTZE RIVER PHARMACEUTICAL GROUP 2012-04-04 CN claimed
CN-100393726-C Process for preparing 2,4-disubstituted heterocyclo [4,5-e][1,2,4] thiadiazine derivatives UNIV SHANDONG (CN) 2008-06-11 CN claimed
CN-1837216-A Process for preparing 2,4-disubstituted heterocyclo [4,5-e][1,2,4] thiadiazine derivatives UNIV SHANDONG (CN) 2006-09-27 CN claimed
EP-0272674-B1 PROCESS FOR PRODUCING 2,6-DICHLOROBENZYL ALCOHOL HODOGAYA CHEMICAL CO., LTD. (JP) 1993-03-17 EP claimed
US-4822924-A REACTING 2,6-DICHLOROBENZYL CHLORIDE WITH SODIUM ACETATE, THEN HYDROLYZING; QUATERNARY AMMONIUM SALTS AS PHASE TRANSFER AGENTS HODOGAYA CHEMICAL CO., LTD. (JP) 1989-04-18 US claimed
EP-0272674-A2 Process for producing 2,6-dichlorobenzyl alcohol HODOGAYA CHEMICAL CO., LTD. (JP) 1988-06-29 EP claimed
EP-0132865-A1 Alpha-halogenated aromatic compounds as photoinitiators STAUFFER CHEMICAL COMPANY (US) 1985-02-13 EP claimed
US-4450298-A Vapor phase catalytic hydrolysis of benzal chloride or its halogen- or trifluoromethyl-substitute to form benzaldehyde or substitute CENTRAL GLASS COMPANY, LIMITED (JP) 1984-05-22 US claimed
US-4248779-A REACTING CARBONYL SULFIDE WITH A SECONDARY AMINE AND REACTING THE AMINE SALT WITH A HALOHYDROCARBON IHARA CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 1981-02-03 US claimed