Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12289742 | 0.82 | MAPT (0.46) | MAPTCYP1A2CYP3A4KDM4ELMNA | |
| SCHEMBL2626890 | 0.81 | MAPT (0.50) | MAPTCYP1A2CYP3A4KDM4ELMNA | |
| SCHEMBL3472206 | 0.77 | KDM4E (0.48) | MAPTCYP1A2CYP3A4KDM4ELMNA | |
| SCHEMBL2626881 | 0.73 | CYP3A4 (0.53) | MAPTCYP1A2CYP3A4KDM4ELMNA | |
| SCHEMBL13048470 | 0.70 | CYP1A2 (0.55) | MAPTCYP1A2CYP3A4KDM4ELMNA | |
| SCHEMBL11394548 | 0.69 | CYP1A2 (0.79) | MAPTCYP1A2CYP3A4KDM4ELMNA | |
| SCHEMBL266592 | 0.68 | CYP3A4 (0.61) | MAPTCYP1A2CYP3A4KDM4ELMNA | |
| SCHEMBL2626892 | 0.68 | CYP1A2 (0.75) | MAPTCYP1A2CYP3A4KDM4ELMNA | |
| SCHEMBL13048785 | 0.67 | CYP1A2 (0.51) | MAPTCYP1A2CYP3A4KDM4ELMNA | |
| SCHEMBL11389733 | 0.67 | CYP1A2 (1.00) | MAPTCYP1A2CYP3A4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9339032-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-17 | — | — | US | disclosed |
| US-20140135346-A1 | Novel Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-05-15 | — | — | US | disclosed |
| US-8664229-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2014-03-04 | — | — | US | disclosed |
| US-20120095023-A1 | Novel Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135346-A1 | Novel Heterocyclic Compounds as Pesticides | DDT, PTMS, AADAC | MAPT 4085/4885CYP1A2 897/4885CYP3A4 920/4885 |
| US-20120095023-A1 | Novel Heterocyclic Compounds as Pesticides | DDT, PTMS, AADAC | MAPT 4085/4885CYP1A2 897/4885CYP3A4 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.