Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.88 |
| ▸ | BCR | P11274 | 13/20 | 0.88 |
| ▸ | KIT | P10721 | 12/20 | 0.88 |
| ▸ | PDGFRA | P16234 | 10/20 | 0.88 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.88 |
| ▸ | ABL2 | P42684 | 3/20 | 0.88 |
| ▸ | EGFR | P00533 | 2/20 | 0.88 |
| ▸ | PLK4 | O00444 | 1/20 | 0.88 |
| ▸ | DDX3X | O00571 | 1/20 | 0.88 |
| ▸ | GAK | O14976 | 1/20 | 0.88 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.88 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.88 |
| ▸ | CA12 | O43570 | 1/20 | 0.88 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.88 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.88 |
| ▸ | CA1 | P00915 | 1/20 | 0.88 |
| ▸ | CA2 | P00918 | 1/20 | 0.88 |
| ▸ | LMNA | P02545 | 1/20 | 0.88 |
| ▸ | ALB | P02768 | 1/20 | 0.88 |
| ▸ | RAF1 | P04049 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31553098 | 0.97 | ABL1 (0.94) | ABL1BCRKITPDGFRAPDGFRB | |
| SCHEMBL12127861 | 0.96 | ABL1 (0.90) | ABL1BCRKITPDGFRAPDGFRB | |
| Imatinib SCHEMBL4081015 | 0.94 | ABL1 (0.92) | ABL1BCRKITPDGFRAPDGFRB | |
| SCHEMBL23817781 | 0.94 | ABL1 (0.86) | ABL1BCRKITPDGFRAPDGFRB | |
| Imatinib SCHEMBL29351601 | 0.94 | ABL1 (1.00) | ABL1BCRKITPDGFRAPDGFRB | |
| SCHEMBL4394235 | 0.94 | ABL1 (0.88) | ABL1BCRKITPDGFRAPDGFRB | |
| Imatinib SCHEMBL29355523 | 0.94 | ABL1 (1.00) | ABL1BCRKITPDGFRAPDGFRB | |
| Imatinib SCHEMBL2236091 | 0.94 | ABL1 (1.00) | ABL1BCRKITPDGFRAPDGFRB | |
| Imatinib SCHEMBL3827 | 0.94 | ABL1 (1.00) | ABL1BCRKITPDGFRAPDGFRB | |
| SCHEMBL4394539 | 0.94 | ABL1 (0.88) | ABL1BCRKITPDGFRAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130203990-A1 | PROCESS FOR THE PREPARATION OF IMATINIB MESYLATE | DR. REDDY'S LABORATORIES, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| WO-2012015999-A2 | PROCESS FOR THE PREPARATION OF IMATINIB MESYLATE | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203990-A1 | PROCESS FOR THE PREPARATION OF IMATINIB MESYLATE | ABL1, ABL2, PDGFRA | ABL1 1/4885BCR 53/4885KIT 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.