Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14689861 | 0.92 | NPC1 (0.61) | CHKAHDAC6NPC1TP53RAB9A | |
| SCHEMBL16356429 | 0.87 | HDAC6 (0.69) | CHKAHDAC6NPC1TP53RAB9A | |
| SCHEMBL65179 | 0.87 | HDAC6 (0.69) | CHKAHDAC6NPC1TP53RAB9A | |
| SCHEMBL14689926 | 0.87 | CHKA (0.58) | CHKAHDAC6NPC1TP53RAB9A | |
| Hydrochloric Acid SCHEMBL3272318 | 0.86 | HDAC6 (0.68) | CHKAHDAC6HRH3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL846616 | 0.86 | HDAC6 (0.68) | CHKAHDAC6HRH3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL14763998 | 0.86 | HDAC6 (0.68) | CHKAHDAC6HRH3MEN1KMT2A | |
| Hydrogen Sulfide SCHEMBL27950422 | 0.85 | HDAC6 (0.62) | CHKAHDAC6NPC1TP53RAB9A | |
| Hydrochloric Acid SCHEMBL3664891 | 0.84 | HDAC6 (0.66) | CHKAHDAC6HRH3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1583152 | 0.84 | HDAC6 (0.66) | CHKAHDAC6HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130203990-A1 | PROCESS FOR THE PREPARATION OF IMATINIB MESYLATE | DR. REDDY'S LABORATORIES, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130203990-A1 | PROCESS FOR THE PREPARATION OF IMATINIB MESYLATE | DR. REDDY'S LABORATORIES, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| WO-2013008242-A1 | A PROCESS FOR THE PREPARATION OF HIGHLY PURE 4-(4-METHYL PIPERAZINOMETHYL) BENZOIC ACID DIHYDROCHLORIDE | NATCO PHARMA LIMITED (IN) | 2013-01-17 | — | — | WO | disclosed |
| WO-2012015999-A2 | PROCESS FOR THE PREPARATION OF IMATINIB MESYLATE | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203990-A1 | PROCESS FOR THE PREPARATION OF IMATINIB MESYLATE | ABL1, ABL2, PDGFRA | CHKA 1893/4885HDAC6 4050/4885NPC1 3354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.