⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863814 | 0.87 | — | — | |
| SCHEMBL8111868 | 0.87 | — | — | |
| SCHEMBL13934690 | 0.79 | — | — | |
| SCHEMBL10577901 | 0.78 | — | — | |
| SCHEMBL27306261 | 0.74 | — | — | |
| SCHEMBL1087661 | 0.72 | — | — | |
| SCHEMBL1088263 | 0.72 | — | — | |
| SCHEMBL11685993 | 0.72 | — | — | |
| SCHEMBL10948785 | 0.69 | — | — | |
| SCHEMBL11006230 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183164-A1 | Synthesis of Vinyl Cyclobutyl Intermediates | AMGEN INC. (US) | 2023-06-15 | — | — | US | disclosed |
| WO-2021226009-A1 | SYNTHESIS OF VINYL CYCLOBUTYL INTERMEDIATES | AMGEN INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| US-10251831-B2 | Extract for treating wrinkles and/or fine lines | AVON PRODUCTS, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-8394427-B2 | Paxillin stimulating compositions and cosmetic uses thereof | AVON PRODUCTS, INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120328546-A1 | Paxillin Stimulating Compositions and Cosmetic Uses Thereof | AVON PRODUCTS, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| US-8168212-B2 | Topical compositions comprising non-proteogenic amino acids and methods of treating skin | AVON PRODUCTS, INC (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110151029-A1 | Paxillin Stimulating Compositions and Cosmetic Uses Thereof | AVON PRODUCTS, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-20100261769-A1 | Topical Compositions Comprising Non-Proteogenic Amino Acids and Methods of Treating Skin | AVON PRODUCTS, INC. (US) | 2010-10-14 | — | — | US | disclosed |
| US-20100160326-A1 | PEST CONTROL AGENT CONTAINING NOVEL PYRIDYL-METHANAMINE DERIVATIVE OR SALT THEREOF | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20100160326-A1 | PEST CONTROL AGENT CONTAINING NOVEL PYRIDYL-METHANAMINE DERIVATIVE OR SALT THEREOF | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-06-24 | — | — | US | disclosed |