Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15632298 | 0.79 | SLC22A8 (0.33) | SELLSELPSELECNR2ESR1 | |
| SCHEMBL11451338 | 0.76 | CNR2 (0.44) | CNR2PTPN1HMGCRCYP3A4TYR | |
| SCHEMBL11451337 | 0.76 | CNR2 (0.44) | CNR2PTPN1HMGCRCYP3A4TYR | |
| SCHEMBL16389630 | 0.76 | CNR2 (0.44) | CNR2PTPN1HMGCRCYP3A4TYR | |
| SCHEMBL27933560 | 0.74 | CNR2 (0.41) | CNR2TYRESR1ESR2ALOX5 | |
| SCHEMBL6254955 | 0.72 | SELL (0.56) | SELLSELPSELECYP3A4ACHE | |
| SCHEMBL18659996 | 0.71 | CYP3A4 (0.41) | CNR2HMGCRCYP3A4TYRACHE | |
| SCHEMBL6555264 | 0.70 | CNR2 (0.45) | CNR2PTPN1HMGCRCYP3A4TYR | |
| SCHEMBL15676303 | 0.70 | HMGCR (0.37) | CNR2HMGCRCYP3A4TYRESR1 | |
| SCHEMBL15676301 | 0.70 | HMGCR (0.37) | CNR2HMGCRCYP3A4TYRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468730-A1 | SUBSTITUTED HYDRAZIDE COMPOUNDS AND APPLICATION THEREOF | Shenyang J & Health Pharmaceutical Co., Ltd. (CN) | 2012-06-27 | — | — | EP | disclosed |