Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.50 |
| ▸ | DPP4 | P27487 | 7/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.50 |
| ▸ | CTSC | P53634 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16999949 | 1.00 | DPP9 (0.50) | DPP9DPP4DPP8DPP7CTSC | |
| SCHEMBL13829067 | 0.82 | DPP7 (0.56) | DPP9DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL23866587 | 0.81 | DPP4 (0.39) | DPP9DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL20649207 | 0.81 | DPP4 (0.39) | DPP9DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL24221417 | 0.81 | DPP9 (0.49) | DPP9DPP4DPP8DPP7ALDH1A1 | |
| SCHEMBL12269108 | 0.81 | DPP4 (0.39) | DPP9DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL17868351 | 0.80 | MME (0.56) | DPP9DPP4DPP8DPP7CTSC | |
| SCHEMBL21748461 | 0.80 | MME (0.56) | DPP9DPP4DPP8DPP7CTSC | |
| SCHEMBL19502439 | 0.80 | DPP4 (0.46) | DPP9DPP4DPP8DPP7CTSC | |
| SCHEMBL21034312 | 0.79 | PTGS1 (0.46) | DPP9DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093231-B2 | Sulfonylethyl phosphorodiamidates | TELIK, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20080039429-A1 | SULFONYLETHYL PHOSPHORODIAMIDATES | TELIK, INC. | 2008-02-14 | — | — | US | disclosed |
| US-7262182-B2 | Sulfonylethyl phosphorodiamidates | TELIK, INC. (US) | 2007-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039429-A1 | SULFONYLETHYL PHOSPHORODIAMIDATES | MTAP, TYMP, PHOSPHO1 | DPP9 187/4885DPP4 53/4885DPP8 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.