⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1345224 | 1.00 | — | — | |
| SCHEMBL4276946 | 1.00 | — | — | |
| SCHEMBL3990776 | 1.00 | — | — | |
| SCHEMBL3990002 | 1.00 | — | — | |
| SCHEMBL3989934 | 1.00 | — | — | |
| SCHEMBL25012457 | 1.00 | — | — | |
| SCHEMBL12341645 | 1.00 | — | — | |
| SCHEMBL3990237 | 1.00 | — | — | |
| SCHEMBL131456 | 1.00 | — | — | |
| SCHEMBL3994476 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220272-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CLOSTRIDIUM ASSOCIATED DISEASE | CAN TECHNOLOGIES, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220281-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF COINFECTION WITH EIMERIA AND CLOSTRIDIUM | CAN TECHNOLOGIES, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20230038480-A1 | SYSTEM FOR PRODUCITON OF HIGH YIELD OF RECOMBINANT PROTEINS | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2023-02-09 | — | — | US | disclosed |
| US-10702497-B2 | Use of acyl-homoserine lactone derivatives as anti-thrombotic agents | THE UNIVERSITY OF TOLEDO (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190111023-A1 | USE OF ACYL-HOMOSERINE LACTONE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | THE UNIVERSITY OF TOLEDO (US) | 2019-04-18 | — | — | US | disclosed |
| US-10195177-B2 | Use of acyl-homoserine lactone derivatives as anti-thrombotic agents | THE UNIVERSITY OF TOLEDO (US) | 2019-02-05 | — | — | US | disclosed |
| US-20180280345-A1 | USE OF ACYL-HOMOSERINE LACTONE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | THE UNIVERSITY OF TOLEDO (US) | 2018-10-04 | — | — | US | disclosed |
| US-9765061-B2 | Trail enhancers for the selective killing of cancer cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170101400-A1 | TRAIL ENHANCERS FOR THE SELECTIVE KILLING OF CANCER CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-04-13 | — | — | US | disclosed |
| US-9604950-B2 | Trail enhancers for the selective killing of cancer cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-03-28 | — | — | US | disclosed |
| US-20110077295-A1 | ANDROGRAPHOLIDE DERIVATIVES AND USE THEREOF IN MANUFACTURE OF MEDICAMENTS | PANORAMA RESEARCH INC. (US) | 2011-03-31 | — | — | US | disclosed |
| US-20100305182-A1 | COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA | BLACKWELL HELEN E | 2010-12-02 | — | — | US | disclosed |
| US-20100305182-A1 | COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA | BLACKWELL HELEN E | 2010-12-02 | — | — | US | disclosed |
| US-7642285-B2 | Compounds and methods for modulating communication and virulence in quorum sensing bacteria | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642285-B2 | Compounds and methods for modulating communication and virulence in quorum sensing bacteria | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-01-05 | — | — | US | disclosed |
| WO-2009018780-A1 | ANDROGRAPHOLIDE DERIVATIVES AND USE THEREOF IN MANUFACTURE OF MEDICAMENTS | PANORAMA RESEARCH INC. (US) | 2009-02-12 | — | — | WO | disclosed |
| US-7384639-B2 | Methods of treating or preventing an infectious disease using an immunogenic conjugate of a gram-negative bacterial autoinducer molecule | UNIVERSITY OF ROCHESTER (US) | 2008-06-10 | — | — | US | disclosed |
| US-7384639-B2 | Methods of treating or preventing an infectious disease using an immunogenic conjugate of a gram-negative bacterial autoinducer molecule | UNIVERSITY OF ROCHESTER (US) | 2008-06-10 | — | — | US | disclosed |
| US-20070231839-A1 | Methods of treating or preventing an infectious disease using an immunogenic conjugate of a gram-negative bacterial autoinducer molecule or antibodies that immunospecifically bind a gram-negative bacterial autoinducer molecule | UNIVERSITY OF ROCHESTER (US) | 2007-10-04 | — | — | US | disclosed |
| US-20070231839-A1 | Methods of treating or preventing an infectious disease using an immunogenic conjugate of a gram-negative bacterial autoinducer molecule or antibodies that immunospecifically bind a gram-negative bacterial autoinducer molecule | UNIVERSITY OF ROCHESTER (US) | 2007-10-04 | — | — | US | disclosed |